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Knee Pain Chronic clinical trials

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NCT ID: NCT06087562 Active, not recruiting - Knee Osteoarthritis Clinical Trials

iPACK Block for Total Knee Arthroplasty

Start date: June 16, 2020
Phase: Phase 4
Study type: Interventional

This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee arthroplasty.

NCT ID: NCT05908942 Active, not recruiting - Knee Pain Chronic Clinical Trials

Genicular RFT vs Phenol Management in Patients With Knee Osteoarthritis

Start date: October 1, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to compare the efficacy of phenol and radiofrequency ablation for genicular nerve neurolysis in severe knee pain. The invesigators compare the efficacy of radiofrequency and phenol applications on numerical pain score and Western Ontario and McMaster Universi- ties Osteoarthritis Index (WOMAC) before, 1 and 3 months after the procedure. The procedures will be performed by applying radiofrequency waves and phenol to the genicular nerves under ultrasound guidance.

NCT ID: NCT05821530 Active, not recruiting - Chronic Pain Clinical Trials

HFIT Versus TENS Study for Chronic Low Back and Knee Pain

Start date: April 24, 2023
Phase: N/A
Study type: Interventional

A high-frequency impulse therapy (HFIT) device (Enso, San Francisco, CA) is a portable device for the treatment of musculoskeletal pain. This three-arm randomized controlled trial study compares a HFIT group to a standard transcutaneous electrical nerve stimulator (TENS) group and a control group.

NCT ID: NCT05791513 Active, not recruiting - Knee Pain Chronic Clinical Trials

The Effectiveness of Using a Clinical Support Tool in Managing Adolescents With Non-Traumatic Knee Pain

MAP-Knee
Start date: May 10, 2023
Phase: N/A
Study type: Interventional

The aim of the stepped-wedge cluster randomised trial is to investigate the effectiveness of using a clinical support tool (The MAP-Knee Tool) in managing adolescents aged 10-19 years with non-traumatic knee pain compared to not using the tool. Six participating hospitals will start to use the tool within 4, 6, or 8 months after recruitment start in a randomised order. We will investigate if using the tool is superior in terms of reducing symptoms compared to not using the tool.

NCT ID: NCT05079035 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

Start date: December 6, 2021
Phase: Phase 2
Study type: Interventional

It is hypothesized that a single Intra-articular Injection of TTAX03, 100mg in 2mL of saline, will have more benefit with respect to the proportion of responders 12 weeks post-injection than an equal volume of saline, based on the OMERACT-OARSI responder criteria.

NCT ID: NCT04885972 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis

Start date: November 15, 2021
Phase: Phase 2
Study type: Interventional

This study evaluates the efficacy and safety of a single IA injection of various RTX doses, Zilretta or placebo for the treatment of pain due to moderate to severe osteoarthritis knee pain..

NCT ID: NCT04817969 Active, not recruiting - Clinical trials for Rheumatoid Arthritis

Persona Ti-Nidium Post-Market Clinical Follow-up

TKA
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The main objectives of this study are to evaluate overall clinical performance and safety of the Persona Ti-Nidium implant in total knee arthroplasty.

NCT ID: NCT04028947 Active, not recruiting - Knee Pain Chronic Clinical Trials

Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty

Start date: January 28, 2020
Phase: N/A
Study type: Interventional

Researchers are trying to determine if knee pain can be reduced by proactively protecting the free end of the saphenous nerve versus leaving it in the standard position during total knee arthroplasty.

NCT ID: NCT03211663 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Performance of MOTO Medial® Unicompartmental Knee Arthroplasty

Start date: October 9, 2017
Phase:
Study type: Observational

This is a prospective, multi-center study, designed to assess mid-term performance of the MOTO Medial® Unicompartmental Knee Arthroplasty (UKA), with patient report outcomes, clinical findings and radiographic analysis.

NCT ID: NCT02255383 Active, not recruiting - Clinical trials for Rheumatoid Arthritis

Persona Total Knee Arthroplasty Outcomes Study

Start date: July 2014
Phase: N/A
Study type: Interventional

The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty. The assessment will include implant survivorship and clinical performance.