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Blood Flow Restriction Training in Individuals Awaiting Total Knee Replacement

Knee Osteoarthritis Clinical Trial

Official title:
Feasibility of Prehabilitation Blood-flow Restriction Training in Individuals Awaiting Total Knee Replacement.

Clinical Trial Summary

The aim is to demonstrate that preoperative exercises (prehabilitation) using blood-flow restriction training (BFRT) is safe, well tolerated, improves muscle function, decreases functional limitation, and increases physical activity in older adults awaiting total knee replacement (TKR).

Clinical Trial Description

Twenty individuals ≥60 years old awaiting TKR due to diagnosis of end-stage knee osteoarthritis who meet the inclusion/exclusion criteria will be invited to participate in a 6 weeks of low-intensity BFRT prehabilitation. We will assess muscle functional (i.e., cross-sectional area and intramuscular fatty content) using computerized tomography, quadriceps muscle strength using an isokinetic dynamometer, a battery of performance-based physical function, self-reported physical function and quality of life, and biomarkers of inflammation using blood serum. Feasibility assessment will be done by looking at safety (i.e., adverse events), compliance, and attrition rate. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06111690
Study type Interventional
Source The University of Texas Health Science Center at San Antonio
Contact Gustavo Almeida, PhD
Phone 210-567-8755
Email almeidag@uthscsa.edu
Status Recruiting
Phase N/A
Start date September 23, 2022
Completion date December 2024
View Details
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