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NCT05340166 Clinical Trial

Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Knee Osteoarthritis Clinical Trial

Official title:
Comparative Evaluation of the Ultrasound-guided Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05340166
Other study ID # 131/01
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 24, 2022
Est. completion date July 5, 2023

Study information
Verified date July 2023
Source Diskapi Teaching and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date July 5, 2023
Est. primary completion date June 20, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Exclusion Criteria: - Coagulation disorders - Rheumatoid disorders - Infections

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Genicular nerve radiofrequency neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves
• Genicular nerve chemical neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Locations
Country Name City State
Turkey Diskapi Yildirim Beyazit Training and Research Hospital Ankara

Sponsors (1)
Lead Sponsor Collaborator
Diskapi Teaching and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Numerical Rating Scale (NRS) Pain Score Change The 11-point NRS consists of numbers between 0 and 10 where 0 indicates "no pain" and 10 indicates "maximum pain." The patient is instructed to identify one number between 0 and 10, which is best representative of their pain intensity. Change from baseline to 6 months after procedure
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