Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Knee Osteoarthritis Clinical Trial

Official title:

Comparative Evaluation of the Ultrasound-guided Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05340166
• Other study ID #: 131/01
• Status: Completed
• Phase: N/A
• Start date: April 24, 2022
• Est. completion date: July 5, 2023

Study information

• Verified date: July 2023
• Source: Diskapi Teaching and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: July 5, 2023
• Est. primary completion date: June 20, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

-

Exclusion Criteria:

• Coagulation disorders

• Rheumatoid disorders

• Infections

Related Conditions & MeSH terms

• Knee Osteoarthritis
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Procedure:
• Genicular nerve radiofrequency neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves
• Genicular nerve chemical neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Locations

Country	Name	City	State
Turkey	Diskapi Yildirim Beyazit Training and Research Hospital	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Diskapi Teaching and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Numerical Rating Scale (NRS)	Pain Score Change The 11-point NRS consists of numbers between 0 and 10 where 0 indicates "no pain" and 10 indicates "maximum pain." The patient is instructed to identify one number between 0 and 10, which is best representative of their pain intensity.	Change from baseline to 6 months after procedure