Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05262049 |
| Other study ID # |
Riphah/RCRS/REC/00862 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
October 18, 2020 |
| Est. completion date |
December 30, 2021 |
Study information
| Verified date |
February 2022 |
| Source |
Riphah International University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
the aim of this study is to compare the effects of intermittent compression decompression
with glides with conventional physical therapy in patients having knee osteoarthritis. there
are three groups in which patient will be allocated randomly. group A will receive treatment
technique intermittent compression decompression with glides only while group B will be
treated with conventional physical therapy protocol whereas group c patients will receive
combination of intermittent compression decompression with glides along with conventional
physical therapy protocol. Pre and post treatment data will be collected by using
questionnaires WOMAC and KOOS. treatment will be given 3 times a week for 4 weeks.
Description:
Most prevalent musculoskeletal age-related disorder worldwide is Osteoarthritis whose
prevalence is supposed to rise in elderly population as it ages. knee pain is common issue
contributing to OA in older population increasing with the increase of risk factor obesity
and as population ages. People with Knee OA experience reduced movement, frequent chronic
pain along with strength and balance compromising and face limitations in daily activities.
Radio graphs of patients with knee OA show changes in lateral and medical tibiofemoral joints
along with patellofemoral joint. Currently, 40% people aged above 75 years are affected with
knee OA. In US, 28% adults older than 45 years of age and 37% older than 65 years of age are
affected with knee OA. Knee osteoarthritis is a major age-related health problem and is
leading cause of pain and disability in people.
Radiographic evidence of osteoarthritis is present in the majority of people over age 65; 80%
of those over 75, Approximately 11% of those over 65 have symptomatic osteoarthritis of the
knee Current guidelines recommend nonpharmacologic methods, such as physical therapy, as
first-line options in the management of OA. Currently there is no medically effective
treatment available. NSAIDS and acetaminophens are widely used to treat this but sometimes
they fail to relieve symptoms leading to more adverse effects. Physical therapy is considered
as an essential element in alleviating pain and improving physical functioning, but the data
is limited. Exercise has showed improvement is walking speed, strength, functions
self-efficacy along with pain alleviation during activities and enables to reduce limitation
of daily. It is an urgent need to identify new effective treatment and techniques for
patients with Knee OA as it is urgent health and clinical priority. Physiotherapy
interventions commonly prescribed for the knee OA management includes electrotherapy along
with knee isometric exercises but these are not as effective as in OA cartilage damages to as
extent along with limited blood flow and reduced metabolic activity. These interventions are
not enough to promote healing response of cartilage. Is supposed to promote osteoblastic
activity, thus improving symptoms along with delaying the degeneration process Intermittent
compression and decompression with glides has significant results in improving symptoms
associated with knee OA along with betterment of quality of life. This technique is believed
to delay and prevent surgical interventions as well as is cost effective treatment for
patients suffering from knee OA.
Mobilization of knee joint includes the mobilization of tibiofemoral joint. This includes
anterior and posterior glides with compression and decompression. Mobilization is a passive
procedure performed to improve pain, increase range of motion and increase functional
capability of patient, because optimal stimulus for the regeneration of the joint cartilage
is intermittent compression and decompression with gliding. Manual physical therapy has also
been reported to inhibit and modulate pain, induce a controlled inflammatory response that
initiates healing and influences processing of pain, and alter acute inflammation in response
to exercise. These could all contribute to decreased pain from muscle contract ion, improving
tolerance for exercise. Joint mobilizations also modulate proprioceptive input to joint
structures, prime the joint and surrounding muscles for optimal response to strengthening
programs, improve muscle control and reaction times. Intermittent compression and
decompression along with gliding of articular cartilage during moderate exercise activities
allows synovial fluid to nourish the joint and remove waste products. This movement can also
lead to thickening and increased resilience in the cartilage. Exercise also leads to
increased muscle and ligamentous strength that provides stability to the joint.
Damaged articular cartilage has less healing capacity due to its low metabolic activity and
limited blood circulation which permit limited response to injury. This cartilage lesion is
sometime very progressive. Therefore, its early intervention is aimed to limit this
progressive lesion to articular cartilage which is may be critical for decreasing the
disability and chronic pain associated with osteoarthritis .Compressive forces applied on the
knee joint pushes the fluid out of cartilage and during decompression it is reabsorbed, this
phenomenon helps in the regeneration of cartilage by means of supplying nutrients and oxygen.
Physical therapy interventions included are electrotherapy along with knee isometric
exercises for management of osteoarthritis. But these interventions are not so effective and
do not help in regeneration of the cartilage. Intermittent compression and decompression with
glide helps to activate osteoblastic activity and improve the symptoms of osteoarthritis thus
delaying the process of degeneration. The study is concerned with finding the effects of
intermittent compression and decompression with glides for the knee osteoarthritis .Treatment
technique in this research will substantially help to improve all the important outcomes as
per literature evident .i.e. pain, disability, range of motion in patients with knee
osteoarthritis. It will add innovative intervention to existing literature which will be
helpful in improving quality of life in patients with knee OA.
