Shock Wave Versus Iontophoresis in Treatment of Subjects With Knee Osteoarthritis

Knee Osteoarthritis Clinical Trial

— Shockwave  

Official title:

Effect of Extra Corporeal Shock Wave Versus Dexamethasone Iontophoresis in Treatment of Knee Osteoarthritis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04731350
• Other study ID #: REC/012/002633
• Status: Completed
• Phase: N/A
• Start date: January 20, 2021
• Est. completion date: January 15, 2023

Study information

• Verified date: March 2023
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Both extra corporeal shock wave and dexamethasone iontophoresisare effective in treatment of knee osteoarthritis but which one is more effective is not clear yet . so the purpose of this study was to investigate and compare between the effect of shock wave and iontophoresis in treatment of knee osteoarthritis . it was hypothesized that there will be no difference between the effect of shock wave and iontophoresis on treatment of knee osteoarthritis.

Description:

60 subjects with grade II knee osteoarthritis will be recruited from outpatient clinic of faculty of physical therapy and then they will be assigned randomly by sealed envelope into three groups ;group A (shock wave group) will received radial extracorporeal shock wave ,group B (Iontophoresis group ) will receive deaxamthasone iontophoresis and group c (control group) will receive traditional tratment ( stregnthening exerciseces) all treatment will be once session per week for four weeks .pain intensity ,knee ROM and knee injury and osteoarthritis outcome score physical function short (KOOS-PS).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: January 15, 2023
• Est. primary completion date: November 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 55 Years

Eligibility

Inclusion Criteria:

1. Symptomatic knee OA for at least 3 months according to clinical criteria of American College of Rheumatology

2. Radiologic findings had to be compatible with knee OA, with kelgren and Lawrence (K-L) grade 2 in a simple X ray .

3. Tenderness on medial tibial plateau

4. Intensity of pain: visual analogue scale equal to 5 or greater

5. Failure of two or more types of previous conservative treatment (medication, anti-inflammatory drugs, physical therapy, stretching, acupuncture, orthotics and others)

Exclusion Criteria:

1. Neuorological and vestibular system disorder, systematic inflammatory disease, steroid injections in the last six months

2. Any contraindication to magnetic resonance imaging or radiography, or trauma history on knee

3. history of previous knee surgery -

Related Conditions & MeSH terms

• Knee Osteoarthritis
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Device:
• radial extracorporeal shock wave
Radial shock wave device, Swiss DolorClast (EMS Electro Medical Systems, Nyon, Switzerland)
• iontophoresis
Iontophoretic drug delivery system (phoresors II auto model PM850 IOMED):

Other:
• Exercise
strengthening exercise

Locations

Country	Name	City	State
Egypt	Faculty of physical therapy ,Cairo University	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	visual analogue scale (VAS)	pain intensity will be assessed by using visual analogue scale	change from baseline to immediately pre treatment and from pre treatment to immediately post treatment
Secondary	knee range of motion (ROM)	electronic geniometer	change from baseline to immediately pre treatment and from pre treatment to immediately post treatment
Secondary	knee injury and osteoarthritis outcome score physical function short (KOOS-PS)	knee function by using KOOS-PS questionnaire	change from baseline to immediately pre treatment and from pre treatment to immediately post treatment