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Autologous Conditioned Serum: Functional and Clinical Results

Knee Osteoarthritis Clinical Trial

Official title:
Autologous Conditioned Serum: Functional and Clinical Results Using a Novel Disease Modifying Agent for the Management of Knee Osteoarthritis

Clinical Trial Summary

The purpose of this study was to investigate the potential ability of autologous conditioned serum (ACS) to decrease the pain and improve the joint functionality in patients affected by knee osteoarthritis (OA).

Clinical Trial Description

Fifteen patients with clinical and radiological signs of OA of the hip or knee were recruited for this study. Each patient received 4 injections of ACS (Orthokine®) at the site of OA once per week for 4 weeks. Clinical and functional evaluation were performed using VAS scale for pain, WOMAC scale and KSS functional and clinical scores before the first injection, at one week, at two weeks, at three weeks, at one month and at six months. Statistical analysis was done with the Wilcoxon Signed-Rank Test. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03850080
Study type Interventional
Source Ospedale San Raffaele
Contact
Status Completed
Phase Phase 2/Phase 3
Start date October 6, 2017
Completion date September 28, 2018
View Details
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