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The Comparison of Efficacy and Safety of the Mesenchymal Stem Cells From Adipose and Hyaluronic Acid

Knee Osteoarthritis Clinical Trial

Official title:
The Comparison of Efficacy and Safety of the Mesenchymal Stem Cells From Adipose and Hyaluronic Acid in the Treatment of Adult Knee Osteoarthritis

Clinical Trial Summary

The aim of this study was to evaluate the efficacy and safety of Mesenchymal Stem Cells (MSCs) from adipose anticular injection in comparison with hyaluronic acid anticular injection in the treatment of human knee osteoarthritis(OA).

Clinical Trial Description

This is a single-centre, quadruple blined, randomized controlled clinical trials with a total of 14 knee osteoarthrits patients as participants, who will be randomly assigned into experiment group or compare group.Participants in experiment group will receive the treatment of MSCs from adipose anticular injection, while participants in compare group will receive hyaluronic acid. Unexplained local and systemic symptoms as well as visual analog scale pain score, WesternOntario McMasterUniversities (WOMAC) Osteoarthritis Index scorewill be assessed at baseline and 2 years after the injection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03357575
Study type Interventional
Source Peking University People's Hospital
Contact Ziyi Yang, MD
Phone 18810335110
Email bjmuyangziyi@163.com
Status Not yet recruiting
Phase N/A
Start date January 1, 2018
Completion date December 1, 2020
View Details
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