Moxibustion in Osteoarthritis of the Knee

Status Completed

Clinical Trial Summary

This is a multicenter , double-blinded, double-dummy, randomized controlled clinical trial to evaluate the efficacy of moxibustion for osteoarthritis of the knee.

Clinical Trial Description

Aim: To evaluate the effectiveness of moxibustion treatment for patients with osteoarthritis of the knee, with respect to relieving pain, improving the dysfunction and improving their quality of life as well.

Design: A multicentre, double-blinded, double-dummy, randomized controlled clinical study will be performed in China. Eligible participants will be randomly assigned to moxibustion group (real moxibustion plus placebo gel) and the control group (diclofenac sodium gel plus sham moxibustion) with a 1:1 allocation ratio. Participants in both groups will receive 12 sessions of real/sham moxibustion in 4 weeks at 3 acupoints (ST35, EX-LE4, ST36 ). Either diclofenac sodium gel or placebo gel will be applied 4 g per knee 4 times daily for 4 weeks. The whole study period is 13 weeks, with a 1-week run-in period, 4-week treatment phase, and 8-week follow-up phase. The primary outcome measure will be the change of the global scale of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at the end of the course. The secondary outcomes include the change of other subscales (pain, stiffness, and function) of WOMAC, Visual Analogue scale (VAS) and Patient Global Assessment (PGA). Safety will be assessed at every visit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02769572
Study type	Interventional
Source	Chengdu University of Traditional Chinese Medicine
Contact
Status	Completed
Phase	Phase 3
Start date	May 2016
Completion date	June 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04651673` - Prescribed Knee Brace Treatments for Osteoarthritis of the Knee (Knee OA)
Completed	`NCT05677399` - Knee Osteoarthritis Treatment With Peloidotherapy and Aquatic Exercise.	N/A
Active, not recruiting	`NCT04043819` - Evaluation of Safety and Exploratory Efficacy of an Autologous Adipose-derived Cell Therapy Product for Treatment of Single Knee Osteoarthritis	Phase 1
Recruiting	`NCT06000410` - A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee	Phase 3
Completed	`NCT05014542` - Needling Techniques for Knee Osteoarthritis	N/A
Recruiting	`NCT05892133` - Prehabilitation Effect on Function and Patient Satisfaction Following Total Knee Arthroplasty	N/A
Recruiting	`NCT05528965` - Parallel Versus Perpendicular Technique for Genicular Radiofrequency	N/A
Active, not recruiting	`NCT03472300` - Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
Active, not recruiting	`NCT02003976` - A Randomized Trial Comparing High Tibial Osteotomy Plus Non-Surgical Treatment and Non-Surgical Treatment Alone	N/A
Active, not recruiting	`NCT04017533` - Stability of Uncemented Medially Stabilized TKA	N/A
Completed	`NCT04779164` - The Relation Between Abdominal Obesity, Type 2 Diabetes Mellitus and Knee Osteoarthritis	N/A
Recruiting	`NCT04006314` - Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis	N/A
Recruiting	`NCT05423587` - Genicular Artery Embolisation for Knee Osteoarthritis II	N/A
Enrolling by invitation	`NCT04145401` - Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK
Active, not recruiting	`NCT03781843` - Effects of Genicular Nerve Block in Knee Osteoarthritis	N/A
Completed	`NCT05974501` - Pre vs Post Block in Total Knee Arthroplasty (TKA)	Phase 4
Completed	`NCT05324163` - Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis	Phase 3
Completed	`NCT05529914` - Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis	N/A
Recruiting	`NCT05693493` - Can Proprioceptive Knee Brace Improve Functional Outcome Following TKA?	N/A
Not yet recruiting	`NCT05510648` - Evaluation of the Effect of High-intensity Laser Therapy in Knee Osteoarthritis	N/A