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Osteoarthritis in Older Adults: Recovery of Mobility and Pain With a Topical Analgesic

Knee Osteoarthritis Clinical Trial

Official title:
Osteoarthritis in Older Adults: Recovery of Mobility and Pain With a Topical Analgesic

Clinical Trial Summary

Biofreeze® is a topical ointment that has menthol and alcamphor. Its analgesic effect lies in the stimulation of A and C fibers by cold and nociceptive stimulation, respectively, which is produced by menthol, apparently through the newly discovered receptor TRPM8 (Transient Receptor Potential melastatin-8) The aim of this study is to investigate if BIOFREEZE ® treatment (Performance Health Inc., Export, PA) improves symptoms associated with moderate knee osteoarthritis, which would decrease the immobility and isolation in older adults.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01565070
Study type Interventional
Source University of Chile
Contact
Status Withdrawn
Phase Phase 3
Start date April 2012
Completion date December 2012
View Details
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