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Exercise and Pain Sensitivity in Knee Osteoarthritis

Knee Osteoarthritis Clinical Trial

Official title:
Exercise and Changes in Pain Sensitivity in Patients With Knee Osteoarthritis

Clinical Trial Summary

A commonly administered conservative non-pharmacological treatment for OA is exercise, with beneficial effects in terms of reduced pain and disability.

While the link between exercise and reduced disability is mediated by e.g. increased muscle strength and endurance, the analgesic mechanisms related to exercise are unexplored. knee OA patients have both peripheral and central sensitization of pain mechanisms resulting in hyperalgesia. Thus, targeted pain treatment in these patients may focus on both peripheral and central mechanisms but it unknown if exercise affects either of these mechanisms.

It is hypothesized that in knee OA patients exercise reduces the pain sensitivity

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01545258
Study type Interventional
Source Frederiksberg University Hospital
Contact
Status Completed
Phase N/A
Start date March 2012
View Details
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