Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome

Insulin Resistance Clinical Trial

Official title:

Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome Before and After Surgical Treatment

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00682084
• Other study ID #: MM-ISC-20070131
• Status: Terminated
• Phase: N/A
• First received: May 20, 2008
• Last updated: December 21, 2017
• Start date: April 2008
• Est. completion date: November 2016

Study information

• Verified date: December 2014
• Source: University of Aarhus
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to investigate the effect og chronic elevated levels of cortisol on metabolism and insulin sensitivity.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 1
• Est. completion date: November 2016
• Est. primary completion date: November 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Written consent

• Age between 18 and 70

• Diagnosed with Cushing's syndrome

Exclusion Criteria:

• Suspected malignancy

Related Conditions & MeSH terms

• Cushing Syndrome
• Cushing's Syndrome
• Hypersensitivity
• Insulin Resistance
• Syndrome

Intervention

Procedure:
• Surgery
Surgical removal of either a pituitary or ectopic ACTH producing tumor or an adrenal tumor

Locations

Country	Name	City	State
Denmark	Department of Endocrinology	Aarhus C	Aarhus

Sponsors (2)

Lead Sponsor	Collaborator
University of Aarhus	Aarhus University Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Insulin sensitivity		Before and after treatment
Secondary	Glucose tolerance, QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism.		Before and after treatment