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Ingestive Microstructure clinical trials

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NCT ID: NCT04933305 Completed - Obesity Clinical Trials

Microstructure of Ingestive Behavior and Body Weight Loss After Roux-en-Y Gastric Bypass

Drinkometer
Start date: April 1, 2019
Phase:
Study type: Observational

Studies of appetitive behavior in humans after RYGB have produced ambiguous results. It therefore remains unclear whether there are fundamental shifts in the palatability of high-fat and sugary foods after RYGB or simply a decrease in the appetitive drive to ingest them. Moreover, learning processes may play a role as changes in diet selection progress with time in rats after RYGB. However, direct measures of an altered food selection in humans after RYGB are rare and both the durability of the phenomenon as well as the role of experience for changes in food selection remain elusive.

NCT ID: NCT03747445 Completed - Obesity, Morbid Clinical Trials

Microstructural Analysis of Ingestive Behavior After Roux-en-Y Gastric Bypass - Pilot

Start date: February 1, 2018
Phase:
Study type: Observational

The ability to assess ingestion in fine detail over the time course of a liquid meal allows for comparison of early and late meal features of drinking and may help dissociate manipulations (surgical, neural, pharmacological, etc.) that affect orosensory properties from those that are modulating postoral processes in the control of intake. The aim of the study is to asses microstructural changes in liquid meal intake over 1-year in severely obese patients after Roux-en-Y gastric bypass (RYGB).