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Influenza, Human clinical trials

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NCT ID: NCT00961337 Completed - Influenza Clinical Trials

Evaluation of a School-based Influenza Vaccination Program

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether inactivated influenza vaccines are effective to protect school children and their households from getting influenza infection and further prevent student's absenteeism.

NCT ID: NCT00959465 Completed - Influenza Clinical Trials

A/H1N1 Immunogenicity and Safety in Adults

Start date: August 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to obtain immunogenicity and safety data at different dose levels of an investigational H1N1 pandemic influenza vaccine in healthy adults 18 years of age and older.

NCT ID: NCT00959049 Completed - Influenza Clinical Trials

A Study to Determine the Immunogenicity and Safety Profile of CSL Limited's Influenza Virus Vaccine Compared to a US Licensed Comparator Influenza Virus Vaccine in a Pediatric Population

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the immunogenicity and safety profile of CSL Limited's Influenza Virus Vaccine compared to a US licensed comparator Influenza Virus Vaccine in a pediatric population aged greater than or equal to 6 months to less than 18 years.

NCT ID: NCT00958243 Completed - Influenza Clinical Trials

A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in a Healthy Pediatric Population in the USA

Start date: August 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity and safety profile of CSL425 (CSL's 2009 H1N1 influenza vaccine) in a healthy pediatric population.

NCT ID: NCT00958126 Completed - Influenza Clinical Trials

A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Adults in the USA

Start date: August 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether CSL425 is a safe and effective vaccine for eliciting an immune response to H1N1 influenza in healthy adults

NCT ID: NCT00957996 Completed - Fatigue Clinical Trials

Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza

Start date: October 2009
Phase: Phase 3
Study type: Interventional

This is a Phase 3, open-label, randomized study of the antiviral activity, safety, and tolerability of intravenous Peramivir in hospitalized subjects with confirmed or suspected influenza infection.

NCT ID: NCT00956761 Completed - Seasonal Influenza Clinical Trials

Safety and Immunogenicity of a Surface Antigen, Inactivated, Adjuvanted With MF59C.1, Seasonal Influenza Vaccine, Formulation 2009-2010

Start date: June 2009
Phase: Phase 2
Study type: Interventional

This is a trial for annual registration of the updated seasonal influenza vaccine formulation.

NCT ID: NCT00956449 Completed - Influenza Clinical Trials

Safety and Immunogenicity of Influenza Vaccine (Surface Antigen, Inactivated) [Ph.Eur], Formulation 2009-2010, When Administered to Non-Elderly Adult and Elderly Subjects

Start date: June 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the antibody response to each of the three influenza vaccine strains included in the licensed seasonal flu vaccine, as measured by hemagglutination inhibition (HI) at 21 days post immunization in non−elderly and elderly subjects in compliance with the requirements of the current European Union (EU) recommendations for the evaluation of the immunogenicity for a new formulation of a licensed flu vaccine (CPMP/BWP/214/96).

NCT ID: NCT00956202 Completed - Influenza Clinical Trials

A Study of Inactivated Swine-Origin A/H1N1 Influenza Vaccines in Healthy European Subjects Aged 3 to 17 Years

Start date: August 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to generate data on immunogenicity and safety of the monovalent H1N1 vaccine in support of the development and registration. Primary objectives: - To describe the immune response to vaccines 21 days after each vaccination in all participants. - To describe the antibody persistence eight months after the first vaccine administration using HAI method, in a subset of participants who received two injections. - To describe the immune response against the A/H1N1 strain using HAI method 21 days after a vaccination with the 2010-2011 NH seasonal TIV administered approximately 13 months after the first vaccination in the subset of participants who received two injections. - To describe the safety profile of each vaccine in all participants.

NCT ID: NCT00956111 Completed - Influenza Clinical Trials

A Clinical Trial With Influenza A/H1N1 Vaccines

Start date: July 2009
Phase: Phase 4
Study type: Interventional

A single center, stratified, randomized and double-blind phase IV clinical trial is to be conducted in healthy elders (equal to or more than 61 years), adults (18-60 years), adolescents (12-17 years) and children (3-11 years) to evaluate the safety and immunogenicity of Sinovac's split-virion or whole-virion novel influenza A (H1N1) vaccines.