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Relationship Between LRG and Periodontal Disease

Inflammation Clinical Trial

Official title:
Leucin-rich alpha2 Glycoprotein (LRG): A Novel Acute Phase Protein Related With Stage 3 Periodontitis

Clinical Trial Summary

This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-α in patients with periodontitis before and after non-surgical periodontal treatment.

Clinical Trial Description

Twenty-five stage 3 periodontitis and twenty-five periodontally healthy individuals were enrolled in the study. Clinical periodontal measurements were recorded; periodontitis patients received non-surgical periodontal treatment, and GCF and serum samples were obtained at baseline and at 6 weeks after treatment. LRG, IL-6 and TNF-α were determined by ELISA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04383561
Study type Interventional
Source Aydin Adnan Menderes University
Contact
Status Completed
Phase N/A
Start date September 30, 2019
Completion date February 15, 2020
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