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NCT03125655 Clinical Trial

Regulation of Inflammatory Genes in Psoriasis

Inflammation Clinical Trial

Official title:
Regulation of Inflammatory Genes in Psoriasis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03125655
Other study ID # F120628003
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date April 22, 2014
Est. completion date April 28, 2027

Study information
Verified date March 2024
Source University of Alabama at Birmingham
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Recruitment information / eligibility
Status Recruiting
Enrollment 13
Est. completion date April 28, 2027
Est. primary completion date April 10, 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 19 Years to 99 Years
Eligibility Inclusion Criteria: - Clinical diagnosis of psoriasis - Must be age 19 or older. - Must be Fitzpatrick skin type I, II, III, IV, V, VI. Exclusion Criteria: - Subjects who do not have photosensitive disease and are not on photosensitizing medications. - Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy). - Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants. - Subjects who are pregnant.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Inflammatory markers

Locations
Country Name City State
United States The Kirklin Clinic Birmingham Alabama

Sponsors (1)
Lead Sponsor Collaborator
University of Alabama at Birmingham

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Inflammatory genes TNF-alpha , IFN-alpha , IL-6, IL-8, IL-12 , IL-23, IL-4, IL-5 and IL-10 1 day
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