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Adavanced Glycated Endproducts and Development of CAD — AGENDA  

Inflammation Clinical Trial

Official title:
Study of Serum Level of Advanced Glycated Endproducts and Development of Coronary Atherosclerosis in Patients Undergoing Coronary Angiogram

Clinical Trial Summary

Blood sample is prospectively taken from consecutive patients underwent coronary angiogram in our center, after getting informed consent from the patients. Serum level of advanced glycation end products (AGEs) was measured and the clinical features of patients (including angiographic results) were entered into our database. Clinical follow-up was performed for all patients, and the relationship between AGEs and paitents' outcome were analyzed. Further intervention will be adjusted according to the results,including clinical and basic research in lab.

Clinical Trial Description

Serum levels of HMGB1, HMGB2, ADAM10, etc. will be measured in lab and animal studies will be designed to intervene the adverse interaction between abnormal serum concentration of AGEs, etc. and worse clinical results. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02089360
Study type Observational [Patient Registry]
Source Shanghai Jiao Tong University School of Medicine
Contact Qi Zhang, PhD
Phone 86-21-64370045
Email rjheart@gmail.com
Status Recruiting
Phase N/A
Start date January 2014
View Details
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