Research on Emissions, Air Quality, Climate and Cooking Technologies in Northern Ghana

Inflammation Clinical Trial

— REACCTING  

Official title:

Research on Emissions, Air Quality, Climate and Cooking Technologies in Northern Ghana

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04633135
• Other study ID #: REACCTING
• Secondary ID: GEO-1211668RD-83
• Status: Completed
• Phase: N/A
• Start date: January 1, 2012
• Est. completion date: December 31, 2017

Study information

• Verified date: November 2020
• Source: University of Colorado, Boulder
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

REACCTING (Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana) is an interdisciplinary randomized cookstove intervention study in the Kassena-Nankana District of Northern Ghana. The study tests two types of biomass burning stoves that have the potential to meet local cooking needs and represent different "rungs" in the cookstove technology ladder: a locally-made, low-tech Gyapa rocket stove and the imported, highly efficient Philips gasifier stove. Intervention households were randomized into four different groups, three of which received different combinations of two improved stoves, while the fourth group serves as a control for the duration of the study. Diverse measurements assess different points along the causal chain linking the intervention to final outcomes of interest. The investigators assess stove use and cooking behavior, cooking emissions, household air pollution and personal exposure, health burden, and local to regional air quality. Integrated analysis and modeling will tackle a range of interdisciplinary science questions, including examining ambient exposures among the regional population, assessing how those exposures might change with different technologies and behaviors, and estimating the comparative impact of local behavior and technological changes versus regional climate variability and change on local air quality and health outcomes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200
• Est. completion date: December 31, 2017
• Est. primary completion date: December 31, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A to 55 Years

Eligibility

Inclusion

Individual Participants:

• Classified as "rural"
• Uses biofuel as main cooking fuel source (firewood, animal waste, crop residue/sawdust)
• Uses borehole as main water source (to facilitate social network analysis linking household's knowledge and attitudes toward stoves to experience of social contacts);
• Does not have electricity (to permit possible addition of lighting intervention at a later date);
• Has a woman in household aged 18-55 and at least one child under five (since women and children are the most vulnerable to cookstove smoke and are thus the main focus of our health measures).

Clusters:

• No more than 25% classified as urban
• Accessible year-round (determined by field staff)
• Having at least 10 eligible households (in line with the participant criteria above)

Exclusion:

• Household could not be located
• Household declined to participate

Related Conditions & MeSH terms

• Growth Retardation
• Inflammation

Intervention

Device:
• Philips stove
Philips Smokeless stove HD4012LS
• Gyapa stove
Wood stove made in Ghana

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
University of Colorado, Boulder	Environmental Protection Agency (EPA), U.S. National Science Foundation

References & Publications (1)

Dickinson KL, Kanyomse E, Piedrahita R, Coffey E, Rivera IJ, Adoctor J, Alirigia R, Muvandimwe D, Dove M, Dukic V, Hayden MH, Diaz-Sanchez D, Abisiba AV, Anaseba D, Hagar Y, Masson N, Monaghan A, Titiati A, Steinhoff DF, Hsu YY, Kaspar R, Brooks B, Hodgson A, Hannigan M, Oduro AR, Wiedinmyer C. Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana (REACCTING): study rationale and protocol. BMC Public Health. 2015 Feb 12;15:126. doi: 10.1186/s12889-015-1414-1. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Health (Biomarkers of inflammation)	Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).	At baseline
Primary	Health (Biomarkers of inflammation)	Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).	At 6 months
Primary	Health (Biomarkers of inflammation)	Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).	At 12 months
Primary	Health (Biomarkers of inflammation)	Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).	At 18 months
Primary	Height	Height of participants	At baseline
Primary	Height	Height of participants	At 6 months
Primary	Height	Height of participants	At 12 months
Primary	Height	Height of participants	At 18 months
Primary	Weight	Weight of participants	At baseline
Primary	Weight	Weight of participants	At 6 months
Primary	Weight	Weight of participants	At 12 months
Primary	Weight	Weight of participants	At 18 months
Primary	Mid-arm circumference	Measurement of mid-upper arm circumference of participants	At baseline
Primary	Mid-arm circumference	Measurement of mid-upper arm circumference of participants	At 6 months
Primary	Mid-arm circumference	Measurement of mid-upper arm circumference of participants	At 12 months
Primary	Mid-arm circumference	Measurement of mid-upper arm circumference of participants	At 18 months
Secondary	Personal exposure to fine particulate matter (PM2.5)	48 hour integrated personal PM2.5 concentrations from filter measurements	48 hour deployment periods
Secondary	Personal exposure to carbon monoxide (CO)	Daily average and integrated personal CO concentrations	48 hour deployment periods
Secondary	Kitchen area concentrations of carbon monoxide (CO)	Daily average and integrated kitchen area CO concentrations	48 hour deployment periods
Secondary	Kitchen area concentrations of fine particulate matter (PM2.5)	48 hour integrated kitchen area PM2.5 concentrations from filter measurements	48 hour deployment periods
Secondary	Self-reported stove usage	Surveys administered to respondents (primary cooks)	At baseline
Secondary	Self-reported stove usage	Surveys administered to respondents (primary cooks)	At 6 months
Secondary	Self-reported stove usage	Surveys administered to respondents (primary cooks)	At 12 months
Secondary	Self-reported stove usage	Surveys administered to respondents (primary cooks)	At 18 months
Secondary	Stove usage as measured by devices	Continuous stove usage indicators as measured by temperature loggers on stoves	Throughout data collection period, approximately 2 years.