Infertility Clinical Trial
Official title:
Novel Approach of Semen Preparation to Improve ICSI Outcome.
The investigators evaluate the feedback of using swim down semen processing method during preparation for ICSI and compare the results of pregnancy and embryos quality with the cases used density gradient method for their semen processing.
Status | Completed |
Enrollment | 890 |
Est. completion date | January 2014 |
Est. primary completion date | September 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 20 Years to 38 Years |
Eligibility |
Inclusion Criteria: all semen samples fresh or frozen that has, - Cases have semen examination criteria fall within WHO 2010 standards of count - Cases have semen examination criteria fall within WHO 2010 standards of motility - Cases have semen examination criteria with all types of abnormal forms - Cases produced more than 4 mature oocytes (M2) and more Exclusion Criteria: - Cases have semen examination criteria with motility less than 5% - Cases have semen examination criteria with count less than 1.0 million - Cases with TESE, TESA and EPSA, both fresh and frozen - Cases produced less than 4 mature oocytes (M2) |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
Bahrain | Al Baraka Fertility Hospital | Manama | Adliyah |
Egypt | Ibn Sina IVF Center- Ibn Sina Hospital | Sohag |
Lead Sponsor | Collaborator |
---|---|
Ahmad Mustafa Mohamed Metwalley |
Bahrain, Egypt,
Malvezzi H, Sharma R, Agarwal A, Abuzenadah AM, Abu-Elmagd M. Sperm quality after density gradient centrifugation with three commercially available media: a controlled trial. Reprod Biol Endocrinol. 2014 Dec 2;12:121. doi: 10.1186/1477-7827-12-121. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Total Pregnancy Rate | Percentage of Pregnancies developed after embryo transfer, for maternal age less than 38 years old. | 3 Years | Yes |
Secondary | Blastulation Rate (BR) | Percentage of blastocyst embryos produced from cleaved embryos, for maternal age less than 38 YO. | 3 years | Yes |
Secondary | Blastocyst formation Rate (BFR) | Developed embryos developed to Blastocyst stage from cleaved embryos. | 3 Years | Yes |
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