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NCT06342856 Clinical Trial

Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia

Infertility Unexplained Clinical Trial

— infertility  

Official title:
Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia a Placebo Controlled Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06342856
Other study ID # idiopathic infertility
Secondary ID
Status Recruiting
Phase Early Phase 1
First received
Last updated
Start date June 15, 2023
Est. completion date July 1, 2024

Study information
Verified date August 2023
Source Ain Shams University
Contact waleed,mo abdelhamid, ass lecturer
Phone 01013340534
Email drwaleedabdelhamid@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia

Description:

Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia a placebo controlled clinical trial

Recruitment information / eligibility
Status Recruiting
Enrollment 120
Est. completion date July 1, 2024
Est. primary completion date June 1, 2024
Accepts healthy volunteers No
Gender Male
Age group N/A and older
Eligibility Inclusion Criteria: - of in¬fertility of 1 year or more without the use of contraception Exclusion Criteria: - o Active genital infections. - Patients with ejaculatory dysfunction - Azoospermia

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• co enzyme Q10 , L- Carnitine
Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Locations
Country Name City State
Egypt Ain Shams University Cairo

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Salvio G, Cutini M, Ciarloni A, Giovannini L, Perrone M, Balercia G. Coenzyme Q10 and Male Infertility: A Systematic Review. Antioxidants (Basel). 2021 May 30;10(6):874. doi: 10.3390/antiox10060874. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Changes in Semen analysis parameters compared to baseline Changes in Semen analysis parameters compared to baseline 6 months
Secondary Serum hormone levels ([FSH], [LH], testosterone, and prolactin) levels compared to baseline and Cost analysis Serum hormone levels ([FSH], [LH], testosterone, and prolactin) levels compared to baseline and Cost analysis 6 moths
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