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NCT ID: NCT05012592 Completed - Malnutrition, Child Clinical Trials

Reducing Malnutrition and Helminthic Infectious Disease Among Primary School Children by the School Nurses

Start date: September 17, 2021
Phase: N/A
Study type: Interventional

Title: Reducing malnutrition and helminthic infectious disease among primary school children by the school nurses: School-based non-randomized study in a developing country Introduction: Globally, malnutrition alone with the infectious disease a widespread problem among primary school (5 to 12 years) children. Infectious diseases such as worm infestations are aggravated with nutritional disorders which most often lead to anemia and several complications. The prevalence of malnutrition and intestinal worm infestation/ helminthic infection is still high and the awareness level of those issues is immensely poor. However, there are limited studies that evaluated the impact of increasing health awareness by the development of the Health Awareness Program for Primary School Children (HAPSC) which is conducted by the experimentally placed school nurse in Bangladesh. Objective: To increase health awareness and knowledge towards reducing malnutrition and intestinal worm infestation by implement and evaluate the impact of the Health Awareness Program for Primary School children (HAPSC) in Bangladesh. Methods: Design: A prospective, open-label, parallel-group (1:1), cluster non-randomization controlled trial (NRCT) Site and sample: School children from four primary schools in the rural areas of North Matlab at Chandpur district at Chittagong division in Bangladesh. Duration: The duration of this study is from August 2021 to March 2024 (32nd months). Outcome variables: Primary: changes in malnutrition among primary school children. Secondary: Evaluate and reduce the prevalence of intestinal worm infestation, increase awareness and knowledge regarding malnutritional and intestinal worm infestation, improvement of health behavior (eating and hygiene), frequency of school absent days, and health-related quality of life. Conclusion: Health education by the health professional in the school setting may be an effective method for improving health behavior, and increasing awareness and knowledge levels about malnutrition and intestinal worm infestation from early childhood.

NCT ID: NCT05007405 Completed - Articular Disease Clinical Trials

Spectrum of Bacterial Infections in Rheumatology

SIBERIE
Start date: February 12, 2021
Phase:
Study type: Observational

Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are : - To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome - To compare OAI of urinary origin with those with another origin

NCT ID: NCT05007236 Completed - Clinical trials for SARS-CoV-2 Infection

Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Symptomatic Mild COVID-19 Infection.

Start date: September 20, 2021
Phase: Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo-controlled study of RP7214 in patients with symptomatic mild SARS-CoV-2 infection, having at least one high-risk feature (e.g., age > 60 years, hypertension, diabetes mellitus, chronic lung disease, chronic kidney disease, liver disease, cerebrovascular disease, obesity, cancer) for developing severe Covid-19 illness.

NCT ID: NCT05007158 Completed - Clinical trials for Cardiac Implantable Electronic Device Infections

Validation of Procalcitonin as a Biomarker Diagnosing CDI

(DIRT II)
Start date: December 1, 2011
Phase:
Study type: Observational [Patient Registry]

Cardiac device infections (CDI), especially pocket infections, are difficult to be diagnosed. Device pocket infections are not associated with elevated white blood cell count. CRP is only assoziated with a low sensitivity. The diagnosis of a local pocket infection is challenging and relies primarily on the clinical presentation. The prospective DIRT study identified procalcitonin (PCT) among 14 biomarkers as the most promising biomarker to aid the diagnosis of pocket infection. The study aims to validate the proposed PCT cut-off value of 0.05 ng/ml for the diagnosis of pocket infection

NCT ID: NCT05005286 Completed - Vaginal Infection Clinical Trials

Evaluation of Breastmilk Microbiota as a Function for Immunity

Start date: December 1, 2020
Phase:
Study type: Observational

The aim of this study is to evaluate the difference of breast milk microbiota between mothers with and without vaginal infections during pregnancy.

NCT ID: NCT05000307 Completed - SARS-CoV Infection Clinical Trials

Co-Sér: Serological Analysis and Viral Neutralization in People With a Documented COVID-19 Infection

Coser
Start date: July 28, 2020
Phase: N/A
Study type: Interventional

In light of the current coronavirus disease 2019 (COVID-19) pandemic, the investigators want to better study the immunological characteristics of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV2) infections in adults. The investigators invite volunteers to participate in a clinical study to better understand what happens after an infection with SARS-CoV2. By collecting and analysing blood samples of people that were infected, the investigators want to evaluate whether or not the participants had an adaptive immune response with the producting of immunoglobulin. The investigators will evaluate the quality of the antibodies and their neutralising capacity. In a selected patient group with strong antibody response, the investigators will try to reproduce them in the lab after the collection of a larger blood sample (max 72 mL) of, in case of insufficient B-cells, a leucapheresis (after consent of the patient). These antibodies can be used in clinical trials to evaluate whether the investigators can cure patients faster or prevent disease by the utilisation of these antibodies. Aside from the aforementioned information the investigators will also collect clinical data such as: demographic information, medical history, routine lab results, radiographic imaging and medication use. After the completion of the study, the samples will be stored for 30 years with consent of the participants.

NCT ID: NCT05000268 Completed - Clinical trials for COVID-19 Respiratory Infection

Examination of The Effects of Telerehabilitation in Painful Healthcare Workers With and Without COVID-19 Infection

Start date: January 16, 2022
Phase: N/A
Study type: Interventional

In the literature, there are studies examining the effects of telerehabilitation on individuals who have had COVID-19, but studies examining the effects on healthcare workers who have experienced COVID-19 are insufficient. In this study, which is planned to be done, it is aimed to examine the effects of myofascial relaxation technique on pain and other symptoms through telerehabilitation. The aim of the study is to examine the effects of myofascial relaxation technique applied with the telerehabilitation method on pain level, anxiety, depression, sleep, fatigue and kinesiophobia in healthcare workers with and without COVID-19 infection with pain.

NCT ID: NCT04991818 Completed - Clinical trials for Microbial Colonization

MSC - OneBiome UX Pilot Study

OneBiome
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Evaluating the user (pregnant women and parents of young children) experience of the OneBiome consumers value journey service offered to the 1000 days and young children consumers market

NCT ID: NCT04980534 Completed - Covid19 Clinical Trials

Evaluation of the Effectiveness of Therapy for Patients With Covid-19 Using Food Supplements Viusid + Asbrip

Start date: January 8, 2021
Phase: N/A
Study type: Interventional

This is a two-arm, randomized, open label, monocenter, controlled study to evaluate the safety and efficacy of Viusid plus Asbrip in patients with mild and moderate symptoms of respiratory illness caused by Coronavirus 2019 infection.

NCT ID: NCT04977739 Completed - Clinical trials for Cardiovascular Diseases

Research on the Application and Mechanism of New Biological Probes in Biomedicine

Start date: August 3, 2021
Phase:
Study type: Observational

Fluorescence is one of the most commonly used research and detection techniques in the field of biomedical science. The characteristics of fluorescent probe directly affect the performance and application of fluorescence analysis and imaging. Aggregation-Caused Quenching has limited the application of traditional fluorescent probes to some extent. This project intends to systematically evaluate the detection efficiency of new methods through the detection of biomarkers in clinical samples and the comparison with the detection methods of traditional biomarkers, so as to provide theoretical and experimental basis for the establishment of fast and simple biomarker detection technologies with new biological probes.