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Clinical Trial Summary

Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are : - To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome - To compare OAI of urinary origin with those with another origin


Clinical Trial Description

This retrospective study will be conducted on medical files. Patients will be mainly selected on : - A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020. - Adult patients 18 year's old or older - Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features) The followed OAI are not included : - Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis - Brucellosis ; Lyme disease Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators. OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy. - Characteristics of three populations will be compared : - - OAI of urinary origin - - OAI of another origin (skin, etc) - - OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05007405
Study type Observational
Source Centre Hospitalier René Dubos
Contact
Status Completed
Phase
Start date February 12, 2021
Completion date December 31, 2021

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