Ventilator Associated Pneumonia Clinical Trial
Official title:
Comparison Between Different Ventilator Hyperinflation Maneuvers
The hyperinflation ventilator was performed in different modalities and ventilatory adjustments, with total pressure of 40cmH2O. The inspiratory volume, inspiratory time, mean airway pressure, inspiratory and expiratory flow, and bias flow were evaluated.
PURPOSE: To compare different ways of applying ventilator hyperinflation. METHODS: A randomized crossover clinical trial was performed with 30 patients (66.5 ± 17.3 years) with hypersecretion. The ventilator hyperinflation was performed in five ventilatory modalities for five minutes, with an interval of 2 hours, the order being determined by randomization: controlled ventilation at volume (VCV) with constant flow of 20 (VCV20) Lpm and 40 Lpm (VCV40), controlled ventilation pressure ventilation (PCV), controlled pressure ventilation associated with inspiratory time adjustment (PCV + Tins) and support pressure ventilation (PSV). In VCV mode, the volume was increased every 50mL, until reaching a maximum pressure of 40cmH2O. In the pressure controlled modes, the inspiratory pressure was increased every 5 cmH2O until the total pressure reached 40 cmH2O. The inspiratory time was adjusted so that the inspiratory flow reached the baseline. The following variables were evaluated: tidal volume, inspiratory time (Tins), mean airway pressure (Pmean), peak inspiratory flow (PIFR) and expiratory flow (PEFR), PIFR / PEFR and Bias Flow (PEFR-PIFR). ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03937947 -
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
|
||
Not yet recruiting |
NCT04057625 -
Transthoracic Ultrasound in the Diagnosis and Follow-up of Ventilator Associated Pneumonia
|
N/A | |
Not yet recruiting |
NCT03267693 -
Gastrointestinal Complications in Association With Oropharyngeal and Respiratory Infections in Mechanical Ventilation
|
N/A | |
Completed |
NCT00726167 -
Serum Procalcitonin Study in the Management of Ventilated Patients
|
N/A | |
Completed |
NCT02078999 -
Biomarkers in Patients Undergoing Mechanical Ventilation
|
N/A | |
Recruiting |
NCT05124977 -
Antimicrobial Stewardship For Ventilator Associated Pneumonia in Intensive Care
|
N/A | |
Recruiting |
NCT05331885 -
A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2
|
Phase 3 | |
Completed |
NCT05517759 -
Application of VAP Bundle Among ICU Nurses
|
||
Active, not recruiting |
NCT04488510 -
Pathogens Involved in Secondary Infections During Severe Forms of Covid-19 Pneumonia:
|
||
Completed |
NCT03917888 -
Clinical Impact of Lung Ultrasound Monitoring for Diagnosis of VAP
|
N/A | |
Not yet recruiting |
NCT06066489 -
Effect of Educational Program About Preventive Care Bundle for Prevention of Ventilator Associated Pneumonia Among Newborns
|
N/A | |
Completed |
NCT02096328 -
Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia
|
Phase 2 | |
Terminated |
NCT00771719 -
Open Label Pharmacokinetic in Adult Patients With Ventilator-Associated Pneumonia
|
Phase 1 | |
Recruiting |
NCT05696093 -
Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit
|
Phase 3 | |
Recruiting |
NCT05354778 -
HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study
|
N/A | |
Not yet recruiting |
NCT06059040 -
Effect of Eliminating Gastric Residual Volume Monitoring on Ventilator Associated Events
|
N/A | |
Completed |
NCT04563104 -
Lung Ultrasound in Procalcitonin- Guided Antibiotic Discontinuation in Ventilator Associated Pneumonia
|
||
Terminated |
NCT01975350 -
Efficacy Study of Colistimethate Sodium Inhalation in Patients With Ventilator-associated Pneumonia
|
||
Recruiting |
NCT06000761 -
Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
|
N/A | |
Not yet recruiting |
NCT03294837 -
Treatment of Ventilator Associated Pneumonia in Pediatric Intensive Care Unit
|
N/A |