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Infection clinical trials

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NCT ID: NCT02308046 Completed - Vaginal Infection Clinical Trials

Multi-Center Study of New Medications to Treat Vaginal Infections

SMART GIVES
Start date: June 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of terconazole gel in the treatment of vaginal infections

NCT ID: NCT02308033 Completed - Vaginal Infection Clinical Trials

Multi-Center Study of New Medications to Treat Vaginal Infections

SMART GIVES
Start date: June 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of metronidazole gel in the treatment of vaginal infections.

NCT ID: NCT02308007 Completed - Vaginal Infection Clinical Trials

Multi-Center Study of New Medications to Treat Vaginal Infections

SMART GIVES
Start date: June 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of terconazole/metronidazole gel in the treatment of vaginal infections

NCT ID: NCT02307747 Completed - Infection Clinical Trials

Disruption of Circadian Rhythm and Healthcare-related Infection in Patients With Severe Trauma

Start date: February 17, 2015
Phase: N/A
Study type: Interventional

Circadian rhythms, which play crucial roles in physiology, are emerging as important regulators of specific immune functions. Hospitalization in intensive care unit leads to a deep impairment of circadian rhythm. Infection is a frequent event during ICU hospitalization. The investigators hypothesis is that in trauma patients the lack of circadian rhythm variations is associated with the occurrence of infection. The primary aim of the study is to assess the circadian variations of plasma Bmal1 in the occurrence of healthcare related infection during the 30 days after inclusion. The secondary aims are to assess the plasma expression of circadian genes (Clock, Cry1, Per3, and Rev-erba), the production of cytokines in plasma, and the concentration of cortisol, according to the occurrence of an infection.

NCT ID: NCT02306330 Completed - Clinical trials for Bacterial Infections

MALDITOF Versus Routine Clinical Microbiology for Identifying Pathogens; a Randomized Diagnostic Trial

MALDITOF
Start date: December 2014
Phase: N/A
Study type: Interventional

MALDI-TOF MS is capable of directly identifying bacteria and fungi in positive blood cultures, which may be beneficial to patient management. Therefore, MALDI-TOF MS is an important new technology that is becoming routine in developed countries. It is currently unknown whether MALDITOF MS improves diagnostics, costs and patient outcomes in developing countries. This study will assess the clinical impact of a MALDITOF MS system (Maldi Biotyper, Bruker, Germany) in the resource constrained setting of Vietnam and at what cost.

NCT ID: NCT02304770 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia

Start date: January 2015
Phase: Phase 2
Study type: Interventional

The study will examine the effect of aminolaevulinic acid (ALA) photodynamic therapy (PDT) of cervical precancerous lesions in women.

NCT ID: NCT02297815 Completed - Acute Otitis Media Clinical Trials

Comparative Effectiveness of Antibiotics for Respiratory Infections

CEARI
Start date: January 2014
Phase:
Study type: Observational

The purpose of this study is to identify and use patient centered outcomes to compare narrow-spectrum and broad-spectrum antibiotics for the treatment of common acute respiratory tract infections (ARTIs) in children.

NCT ID: NCT02292719 Completed - Clinical trials for Chronic Hepatitis C Virus Infection

A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir With Sofosbuvir With or Without Ribavirin in Adults With Chronic Hepatitis C Virus Infection

Quartz II/III
Start date: December 19, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of Ombitasvir (OBV)/paritaprevir (PTV)/ritonavir (r) with sofosbuvir (SOF) with or without ribavirin (RBV) in adults with Genotype 2 Chronic Hepatitis C Virus (HCV) infection or Genotype 3 HCV infection with or without Cirrhosis.

NCT ID: NCT02292498 Completed - Clinical trials for Pneumonia, Bacterial

Thermal Imaging to Diagnose and Monitor Suspected Bacterial Infections

Start date: November 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to test the feasibility of using thermal images to diagnose bacterial pneumonia instead of a chest x-ray in the future. More specifically, the objectives of this study are: 1) to determine if thermal imaging, using a commercial thermal camera can detect areas of heat emitted from the chest in similar locations to where a chest X-ray shows focal consolidation consistent with bacterial pneumonia; 2) to evaluate whether changes in heat emitted from the chest changes over time if it is possible to obtain serial images of the chest.

NCT ID: NCT02292160 Completed - Clinical trials for Urinary Tract Infection Empiric Antibiotic

Does the National Health Insurance Card Allow us to Predict Antibiotic Resistance?

Start date: September 2015
Phase: N/A
Study type: Observational

The objective is to determine if data from the National Insurance Health card (giving antibiotics and hospitalizations in the past 18 months) allow to predict the individual risk of antibiotic resistance and to identify population groups for which probabilistic antibiotics regimen of urinary tract infection could be simplified