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Infection clinical trials

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NCT ID: NCT03042260 Recruiting - Clinical trials for Lupus Erythematosus, Systemic

Prophylactic Trimethoprim/Sulfamethoxazole to Prevent Severe Infections in Patients With Lupus Erythematous

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether trimethoprim/sulfamethoxazole is effective in preventing serious infectious complications (those that require hospitalization or lead to death) in patients with lupus erythematosus that receive intermediate or high dose steroids.

NCT ID: NCT03042091 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

Start date: September 2016
Phase: Early Phase 1
Study type: Interventional

This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery. Polyethylene glycol, may draw water from the body into the colon, flushing out the contents of the colon. Antibiotics, like neomycin and metronidazole hydrochloride, may stop bacteria from growing. It is not yet known whether it's better to give preoperative neomycin and metronidazole hydrochloride with or without polyethylene glycol in reducing surgical site infection after colorectal surgery.

NCT ID: NCT03040960 Recruiting - Orthopedic Disorder Clinical Trials

Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery

ISO
Start date: August 2016
Phase: N/A
Study type: Observational

The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known. The aim of this study was to evaluated the incidence rate of S. aureus SSI over the years and risk factors of these infections in a french University Hospital.

NCT ID: NCT03038464 Recruiting - Clinical trials for Diagnosis Prosthetic Joint Infection

Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection

SyPJI
Start date: November 1, 2016
Phase: N/A
Study type: Observational

The two-stage protocol is gold standard in terms of infection control treating prosthetic joint infections of total hip and total knee arthroplasty. The antibiotic pause for diagnostic reasons before reconstruction (stage two) is discussed concerning persistence of infection and development of resistant bacterial strains. Serological markers and synovial analysis are common use to exclude persistence of infection. The investigators therefore asked 1) is the serological testing of c-reactive protein and leukocytes a valuable tool to predict a persistence of infection and 2) what is the role of synovial aspiration of PMMA Spacers on hip and knee joints.

NCT ID: NCT03011437 Recruiting - Clinical trials for Helicobacter Pylori Infection

Diagnosis Ability of Linked Color Imaging for Helicobacter Pylori Infection Compared With White Light Imaging

Start date: December 2016
Phase: N/A
Study type: Observational

There are lack of endoscopic criteria for diagnosing Helicobacter pylori (H. pylori) infection by conventional white light imaging (WLI). Linked color imaging (LCI) is a newly developed endoscopy technique, which can diagnose mucosal lesions and H. pylori infection by enhancing color contrast of the mucosa. The aim of the study is to investigate the ability of LCI for diagnosing H. pylori infection compared with WLI.

NCT ID: NCT02985086 Recruiting - Neonatal Infection Clinical Trials

Immediate Versus Delayed Induction in Term-PROM Using or Not Antibiotic Prophylaxis

Start date: July 2013
Phase: N/A
Study type: Interventional

The primary aim of this study is to determine if antibiotics combined with immediate induction can significantly reduce the rate of maternal and neonatal infection compared with immediate induction alone in women presenting with PROM later than the 37+0 weeks of gestation. The secondary aim is to compare the rates of infection between immediate and delayed induction in women submitted to antibiotic prophylaxis.

NCT ID: NCT02976480 Recruiting - Infection Clinical Trials

The Irrigation Or No Irrigation In Simple Lacerations Trials

ION-SiLac
Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the irrigation or non-irrigation of a simple laceration treated in the emergency department has an effect on the subsequent rate of infection.

NCT ID: NCT02959684 Recruiting - HIV Clinical Trials

Strategic Screening for Infectious Diseases (Tuberculosis, HIV, HBV, HCV) Amongst Migrants in France

STRADA
Start date: April 14, 2017
Phase:
Study type: Observational

To evaluate the efficacy of a new screening for infectious diseases: tuberculosis, HIV, HBV and HCV, based on risk factors questionnaires (TB screen for tuberculosis and TROD screen for HIV and hepatitis) amongst a population of legal migrants during their mandatory medical check-up. This study aims for a global improvement of screening and care for migrants.

NCT ID: NCT02950246 Recruiting - Clinical trials for Catheter Related Infection

Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation

CHLOVEPI
Start date: November 2016
Phase: N/A
Study type: Interventional

Implementation of perineural catheters may lead to infection by catheter colonization. Catheters may be colonized by the bacteria present on the skin. This is most often commensal organisms as Staphylococcus or gram negative bacilli. In a large study of 1416 peripheral nerve catheters, 28.7% of catheters were cultured positive. This colonization is most often silent because in the same study only 3% of patients had signs of local inflammation and one psoas abscess was observed (0.07%). The germs are most often coagulase negative staphylococci (61%) and gram negative bacillus (21.6%).

NCT ID: NCT02944695 Recruiting - Infection Control Clinical Trials

Audit of Bronchoscopy Practice in Egypt: Adherence to Safety and Infection Control Guidelines

Start date: October 2016
Phase:
Study type: Observational

Both patient and staff safety are of major importance during the procedure of fibreoptic bronchoscopy. Patient safety depends partly on adequate disinfection of instruments and accessories used as well as careful monitoring during the procedure.