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Infection clinical trials

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NCT ID: NCT01640925 Completed - Clinical trials for Surgical Wound Infection

Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit

Start date: July 2012
Phase: N/A
Study type: Interventional

This prospective, randomized, controlled trial will compare the incidence of nosocomial infections (composite of primary bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and surgical site infections) that occur in intensive care unit (ICU) patients bathed with 2% chlorhexidine solution versus patients who receive standard bathing (soap and water or non-medicated cloths).

NCT ID: NCT01639430 Completed - Infection Clinical Trials

Diagnostic Accuracy of Body Temperature Measurement in Geriatric Patients

Start date: May 2012
Phase: N/A
Study type: Observational

Retrospective analysis of a quality measurement project examining the quality of vital parameter measurement in consecutive patients >= 75 years presenting to the emergency department. Primary goal of the study is to evaluate the diagnostic accuracy of body temperature measurement using different methods to diagnose infection in patients >= 75 years presenting to the emergency department. The secondary goal is to compare the reliability of tympanal and temporal artery thermometry with rectal temperature measurement.

NCT ID: NCT01637870 Completed - Wound Infection Clinical Trials

Negative Pressure Wound Therapy After Cesarean Delivery

Start date: August 2012
Phase: N/A
Study type: Interventional

This study is aimed at determining whether or not the use of a wound suction device placed on the cesarean incision instead of a standard sterile dressing will decrease the prevalence of wound complications and wound infections in women at high risk for post operative complications. The study will first look at the infection and wound complication rate in women 6 months prior to the start date of the study by reviewing charts of women who have undergone a cesarean section. The study involves placing a single use, portable wound vacuum over the cesarean section incision and keeping it in place for 72h. The investigators will then compare the rates of wound infection and wound complications between these two groups. It is our hypothesis that negative pressure wound systems will decrease the wound infection and complication rate in this high risk population.

NCT ID: NCT01634477 Completed - Healthy Clinical Trials

Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort Study

TNT-HIV
Start date: January 2010
Phase:
Study type: Observational

1. To describe the morbidity and clinical characteristics among HIV-infected patients and HIV-uninfected patients. 2. To identify the risk factors for the complication or morbidity among HIV-infected patients and HIV-uninfected patients. 3. To describe the mortality among HIV-infected patients and HIV-uninfected patients. 4. To identify the risk factors for the cause of death among HIV-infected and HIV-uninfected patients.

NCT ID: NCT01631968 Completed - Clinical trials for Infection After Primary Total Knee Arthroplasty

Incidence of Infection After Total Knee Arthroplasty Using an Erythromycin and Colistin Loaded Cement or a Standard Cement

Start date: September 2007
Phase: N/A
Study type: Interventional

Prospective randomized study in cemented primary total knee arthroplasty. In one group the cement used was standard cement, without any antibiotics and in the other group the cement used was loaded with 0.5 g of erythromycin and 3 million units of colistin in 40 g of cement. In all cases intravenous antibiotics prophylaxis against infection was used. In both groups the cement was mechanically mixed in a vacuum. One deep drain tube was placed for 24 hours in all cases. The main variable was the presence of infection according to the Center of Disease Control criteria with a minimum of 12 months follow-up.

NCT ID: NCT01631461 Completed - Breast Infection Clinical Trials

Painful Breastfeeding and Bacterial or Yeast Infection

Start date: December 2006
Phase: N/A
Study type: Observational

The aim of this study is to investigate the prevalence of yeast and bacteria in women with breastfeeding pain and to identify signs and symptoms.

NCT ID: NCT01631201 Completed - Clinical trials for Chlamydia Trachomatis Infection

Safety and Efficacy Study of Rifalazil for the Treatment of Chlamydia Trachomatis Infection in Women

Start date: July 2012
Phase: Phase 2
Study type: Interventional

This study will test the safety and effectiveness of an investigational antibiotic drug, rifalazil for the treatment of uncomplicated genital Chlamydia trachomatis infection. This study will examine the effects of 25 milligram of rifalazil compared with azithromycin 1 gram, which will be given as a single dose to women who have genital chlamydial infection.

NCT ID: NCT01629550 Completed - Clinical trials for Preventing Catheter Related Infection

Prospective Randomized Controlled Multicenter Trial of 4 Antiseptic Strategies for Prevention of Catheter Infection in Intensive Care Unit for Adults Patients

CLEAN
Start date: October 2012
Phase: Phase 4
Study type: Interventional

Catheter related infection is the third cause of nosocomial infection in ICUs. Most of them are avoidable and can be prevent by improving aseptic practices during catheter insertion and maintenance. Indeed, the main route of catheter contamination for short-term catheters is the insertion site. Consequently, the quality of skin disinfection is the most effective preventive measure to reduce the incidence of these infections. This aim of the present study is to compare four strategies of skin disinfection to determine whether a 2% alcoholic solution of chlorhexidine acts better than 5% alcoholic povidone iodine in reducing catheter infection and to assess whether a detersion phase prior to disinfection reduces catheter colonization as compared with no detersion.

NCT ID: NCT01628666 Completed - Arrhythmia Clinical Trials

Prevention of Arrhythmia Device Infection Trial (PADIT)

Start date: December 2012
Phase: Phase 4
Study type: Interventional

The goal of the study is to compare whether a center-wide policy of incremental antibiotic therapy will reduce CIED infection rate compared to a policy of conventional antibiotic prophylaxis in high-risk patients undergoing arrhythmia device procedures. All antibiotics used are approved for use and readily available.

NCT ID: NCT01624948 Completed - BK Virus Infection Clinical Trials

Safety and Efficacy Study of Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients

Start date: September 2012
Phase: Phase 4
Study type: Interventional

This study is examining the safety and efficacy of converting anti-rejection therapy from mycophenolic acid (MPA) to Zortress (everolimus) in renal transplant recipients with BK virus infection. The study will also determine if immune monitoring tests can detect an association between BK virus infection and transplant rejection episodes, based on the specific BKV infection treatment regimen. The investigators hypothesize that an anti-rejection regimen with Zortress (everolimus) and tacrolimus + prednisone will be superior to a standard regimen of reduced dose MPA and tacrolimus + prednisone in patients who have undergone renal transplantation and have active BKV infections.