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Infection clinical trials

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NCT ID: NCT00463086 Completed - HIV Infections Clinical Trials

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons

HAART-IPT
Start date: November 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate whether isoniazid can safely (and further) reduce the risk of tuberculosis in HIV infected people receiving HAART.

NCT ID: NCT00461877 Completed - Clinical trials for Papillomavirus Infections

High-Risk HPV Infections in Women Aged 25 to 65

Start date: March 2007
Phase: N/A
Study type: Observational

The purpose of this study is to determine risk factors for HPV infections in 25 to 65 year old women who report having used internet dating websites in the past year.

NCT ID: NCT00457509 Completed - Pandemic Influenza Clinical Trials

Safety and Immunogenicity of H5N1 Adjuvanted, Inactivated, Split-Virion Pandemic Influenza Vaccine in Healthy Adults

Start date: January 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test different adjuvanted vaccine formulations as a two-dose schedule in immunologically naïve adults against one vaccine formulation without adjuvant in terms of tolerance and immunogenicity Primary Objective: To describe the safety profile and immunogenicity following each injection.

NCT ID: NCT00454272 Completed - Infection Clinical Trials

Comparison of Teicoplanin and Vancomycin in Initial Empirical Antibiotic Regimen for Febrile Neutropenic Patients

Start date: January 2005
Phase: Phase 4
Study type: Interventional

The aim of the study is to evaluate the efficacy and safety of Teicoplanin versus Vancomycin as part of the initial antibiotic regimen in the therapy of patients with fever and neutropenia .

NCT ID: NCT00451386 Completed - Clinical trials for Urinary Tract Infections

Ertapenem Study in Pediatric Patients Who Have Urinary Tract Infections, Skin Infections or Community-acquired Pneumonia (0826-036)

Start date: January 2002
Phase: Phase 2
Study type: Interventional

This study will investigate the safety and efficacy of ertapenem versus ceftriaxone in pediatric patients with urinary tract infections, skin infections, or community-acquired pneumonia.

NCT ID: NCT00450632 Completed - Clinical trials for Meningococcal Infections

Creation of a Biotheque of Patients of Seine-Maritime With Meningococcal Infection

Start date: September 2005
Phase: N/A
Study type: Observational

The main objective of this study is to constitute a biotheque of patients with meningococcal disease to enable results to be interpreted and genetic factors to be determined

NCT ID: NCT00450580 Completed - HIV-1 Infection Clinical Trials

HIV-1 Infection Study of Once a Day Versus Twice a Day Protease Inhibitor in Antiretroviral Treatment Naive Adults

Start date: March 2007
Phase: Phase 3
Study type: Interventional

This is a Phase IIIB, 48 Week, multicentre, randomized, open-label, parallel group study comparing the safety and efficacy of fosamprenavir plus ritonavir 1400mg/100mg once-daily to fosamprenavir plus ritonavir 700mg/100mg twice-daily, both administered with abacavir/lamivudine 600mg/300mg once-daily in antiretroviral-naive HIV-1 infected adults. This study utilizes a group-sequential design with two stages: 1) an interim 24 week cohort analysis of approximately 200 subjects and 2) if study continuation criteria are met at this interim analysis, further enrolment of an additional 528 subjects, followed over a minimum of 48 weeks. The objectives of the study are to demonstrate 1) non-inferior antiviral activity of fosamprenavir/ritonavir 1400mg/100mg QD compared to fosamprenavir/ritonavir 700mg/100mg BID and 2) a superior fasting non-HDL lipid profile in subjects receiving fosamprenavir/ritonavir 1400mg/100mg QD.

NCT ID: NCT00448981 Completed - Clinical trials for Respiratory Tract Infections

Stopping Upper Respiratory Infections and Flu in the Family: The Stuffy Trial

STUFFY
Start date: November 2006
Phase: N/A
Study type: Interventional

Colds and flu cause much loss of work and school. The purpose of this study is to try to reduce the transmission of colds and flu among household members with one of three interventions: some educational material, educational material and use of alcohol hand sanitizers, and educational material and use of alcohol hand sanitizers as well as face masks when somebody has symptoms of the flu. We will recruit 450 households in Northern Manhattan and each household will be randomly assigned to one of these three groups. We will then follow these households for 15 months to see how often they get cold and flu symptoms. We will also look at antibiotic use practices for symptoms of colds and influenza Íž household member knowledge of prevention and treatment strategies for pandemic influenza and viral URIsÍž and rates of influenza vaccination among household members. When someone in the study has serious flu symptoms such as a high fever and cough or sore throat, we will also obtain a nasal culture (by swabbing the nose) to see if there is flu virus present.

NCT ID: NCT00448942 Completed - MRSA Colonization Clinical Trials

The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections

Start date: November 2004
Phase: N/A
Study type: Observational

The purpose of this study was to determine if the use of daily chlorhexidine bathing would decrease the incidence of MRSA and VRE colonization and healthcare associated Bloodstream Infections (BSI) among Intensive Care Unit (ICU) patients.

NCT ID: NCT00448669 Completed - HIV Infections Clinical Trials

Botswana TDF/FTC Oral HIV Prophylaxis Trial

TDF2
Start date: March 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This study tested whether taking a pill of tenofovir and emtricitabine (two antiretroviral medicines) was safe for sexually-active young adults in Botswana without HIV infection and whether it reduced their risk of getting an HIV infection.