Infection, Surgical Site Clinical Trial
Official title:
Intraosseous Vancomycin vs Intravenous Vancomycin in Tourniquetless Primary Total Knee Arthroplasty
Purpose of this study is to compare the efficacy of intravenous and intraosseous antibiotic administration techniques during tourniquetless total knee arthroplasty.
Primary Objective: Comparable levels of vancomycin will be found in distal femur, proximal tibia, and periarticular soft tissues, as well as in systemic levels, between the intravenous and intraosseous administration groups. Secondary Objective: Compare 30- and 90-day post-operative complication rates (infection) between the control (standard IV administration of vancomycin) versus the interventional group (intraosseous administration of vancomycin). The research team hypothesizes that there will be no difference in complication (infection) rates between groups ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05499481 -
Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
|
Phase 3 | |
| Completed |
NCT03659344 -
Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study
|
N/A | |
| Not yet recruiting |
NCT05247086 -
Negative Pressure Therapy After Infected Mesh Removal.
|
N/A | |
| Recruiting |
NCT04541394 -
Effectiveness and Clinical Application of MolecuLight Bacterial Fluorescence Imaging in Wound Debridement
|
N/A | |
| Active, not recruiting |
NCT05873049 -
Use of Real-time Fluorescence Imaging in Diabetic Foot Ulcers: the Impact of Colonization
|
N/A | |
| Completed |
NCT05466604 -
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
|
Phase 4 |