Ileus Clinical Trial
Official title:
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Intravenous Methylnaltrexone (MOA-728) for the Treatment of Post Operative Ileus After Ventral Hernia Repair
This study will evaluate the safety and efficacy of two different dose regimens (12 milligrams [mg] and 24 mg) of IV MOA-728 versus placebo in shortening the time to return of bowel function in participants receiving opioid analgesia administered via patient-controlled anesthesia (PCA), and who had undergone repair of large (greater than or equal to [≥]10 centimeters) ventral hernias with or without a mesh prosthesis via laparotomy or laparoscopy.
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Status | Clinical Trial | Phase | |
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Terminated |
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Phase 2 | |
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Completed |
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Completed |
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Phase 2 | |
Completed |
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Phase 1 | |
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Completed |
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Terminated |
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Not yet recruiting |
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Completed |
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Active, not recruiting |
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N/A | |
Completed |
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Phase 3 | |
Terminated |
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Phase 3 | |
Completed |
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Phase 3 | |
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N/A |