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Evaluation of the Value of 18F-Fluoromisonidazole (18F-FMISO) Positron Emission Tomography Hypoxia Imaging in Idiopathic Pulmonary Fibrosis — FIPOXY  

Idiopathic Pulmonary Fibrosis Clinical Trial

Official title:
Evaluation of the Value of 18F-Fluoromisonidazole (18F-FMISO) Positron Emission Tomography Hypoxia Imaging in Idiopathic Pulmonary Fibrosis - A Non-randomized Proof-of-concept Study Comparing Patients With Idiopathic Pulmonary Fibrosis and Healthy Subjects

Clinical Trial Summary

Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, lethal disease of unknown etiology and with a variable course. There is currently no test in routine care that can assess both the anatomical and functional damage of the disease at an early stage. This is the first human study in IPF to evaluate the value of a non-invasive tracer, 18F-fluoromisonidazole (18F-FMISO), targeting hypoxia in IPF patients. This is a Phase I, proof-of-concept, single-center, open-label, parallel group study. It will include 2 groups: - 1 group of 10 IPF patients - 1 group of 10 healthy volunteers matched to IPF patients for age and gender

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05331729
Study type Interventional
Source Centre Hospitalier Universitaire Dijon
Contact Guillaume BELTRAMO
Phone 03 80 29 37 72
Email guillaume.beltramo@chu-dijon.fr
Status Recruiting
Phase Phase 1
Start date March 20, 2023
Completion date May 2026
View Details
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