Idiopathic Pulmonary Fibrosis Clinical Trial
Official title:
A Comparative Assessment of Measurements Made in an Incremental Shuttle Walk Test and Incremental Cycle Ergometry Test in Patients With Idiopathic Pulmonary Fibrosis
NCT number | NCT03360032 |
Other study ID # | 222072 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | January 10, 2018 |
Est. completion date | April 2020 |
Idiopathic pulmonary fibrosis (IPF) is a chronic and potentially fatal lung disease. As IPF
progresses, patients become increasingly breathless with reduced exercise capacity and
quality of life. A cardiopulmonary exercise test (CPET) is a gold standard way of assessing
patients with IPF.
An incremental shuttle walk test is simpler, cheaper, more widely available and anecdotally
preferable to CPET. The investigators will compare the measurements made in an ISWT and a
CPET in patients with IPF . We aim to determine whether sufficient information can be
gathered in an ISWT to negate the need to undertake CPET.
Status | Recruiting |
Enrollment | 43 |
Est. completion date | April 2020 |
Est. primary completion date | April 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years to 90 Years |
Eligibility |
Inclusion Criteria: - Diagnosis of idiopathic pulmonary fibrosis confirmed by a multi-disciplinary team. - Aged 16 or over - Able to give informed consent to take part - Able to undertake both a cycle ergometry test and an incremental shuttle walk test without needing walking aids Exclusion Criteria: - An inability to give informed consent. - Taking part in a research project with a potentially research-modifying intervention - Currently pregnant. - Currently breastfeeding. - Unable to perform an incremental shuttle walk test. - Unable to perform an incremental cycle ergometry test. - Unable to walk without an aid such as a stick or frame. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University Hospital | Coventry | Warwickshire |
Lead Sponsor | Collaborator |
---|---|
University Hospitals Coventry and Warwickshire NHS Trust |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | VO2 peak | Maximum oxygen consumption at peak exercise | Measured and reported at time of test | |
Secondary | PO2 | Oxygen pressure in capillary blood at peak exercise | Measured and reported at time of test |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05984992 -
The First-in-human Study of SRN-001 in Healthy Participants
|
Phase 1 | |
Active, not recruiting |
NCT04312594 -
Study of Jaktinib Hydrochloride Tablets in Participants With Idiopathic Pulmonary Fibrosis
|
Phase 2 | |
Recruiting |
NCT03865927 -
GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis
|
Phase 2 | |
Completed |
NCT03979430 -
Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study
|
N/A | |
Enrolling by invitation |
NCT04905693 -
Extension Study of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis
|
Phase 3 | |
Terminated |
NCT04419558 -
Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)
|
Phase 3 | |
Completed |
NCT03725852 -
A Clinical Study to Test How Effective and Safe GLPG1205 is for Participants With Idiopathic Pulmonary Fibrosis (IPF)
|
Phase 2 | |
Terminated |
NCT03573505 -
An Efficacy and Safety Study of BG00011 in Participants With Idiopathic Pulmonary Fibrosis
|
Phase 2 | |
Recruiting |
NCT04148157 -
Quality of Life in IPF - Patient and Physician Perceptions
|
||
Completed |
NCT03222648 -
Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis
|
N/A | |
Completed |
NCT02257177 -
RCT (Randomized Control Trial) of TD139 vs Placebo in HV's (Human Volunteers) and IPF Patients
|
Phase 1/Phase 2 | |
Completed |
NCT02268981 -
Effects of an Oxymizer® During Daytime in Patients With Pulmonary Fibrosis (IPF)
|
N/A | |
Withdrawn |
NCT01524068 -
A MultiCenter Study of Combined PEX, Rituximab, and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations
|
Phase 2 | |
Enrolling by invitation |
NCT01382368 -
Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients
|
Phase 4 | |
Completed |
NCT01110694 -
Prospective Observation of Fibrosis in the Lung Clinical Endpoints Study
|
||
Completed |
NCT01199887 -
Trial Of IW001 in Patients With Idiopathic Pulmonary Fibrosis
|
Phase 1 | |
Active, not recruiting |
NCT02951416 -
Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank
|
||
Terminated |
NCT00981747 -
Targeting Vascular Reactivity in Idiopathic Pulmonary Fibrosis
|
Phase 2/Phase 3 | |
Completed |
NCT00540475 -
Pennsylvania Idiopathic Pulmonary Fibrosis Research Registry
|
||
Completed |
NCT00532233 -
SD, IL-13 Production Rate in IPF
|
Phase 2 |