Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP) — BABS

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Hypophosphatasia (HPP) Clinical Trial

Official title:
Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)

Status Active, not recruiting

Clinical Trial Summary

The study aims to evaluate the bone architecture and bone strength in adults with Hypophosphatasia (HPP).

n/a

NCT number	NCT04181164
Study type	Observational
Source	Hvidovre University Hospital
Contact
Status	Active, not recruiting
Phase
Start date	October 1, 2019
Completion date	December 30, 2021

See also
Status	Clinical Trial	Phase
Completed	`NCT00952484` - Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)	Phase 2
Completed	`NCT00744042` - Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)	Phase 1/Phase 2
Completed	`NCT02104219` - Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)
Enrolling by invitation	`NCT02306720` - Registry of Patients With Hypophosphatasia
Completed	`NCT01419028` - A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)
Completed	`NCT00739505` - Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)	Phase 1
Completed	`NCT01203826` - Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)	Phase 2