Scars After Central Venous Catheters

Status Active, not recruiting

Clinical Trial Summary

Most children with cancer need a central venous catheter. These catheters are typically placed on the anterior thorax, where the risk of hypertrophic scarring and keloid development is greatly enhanced. A significant part of the children who have survived childhood cancer are troubled by their scars.

Topical glucocorticoid treatment is known to induce a reduction of the collagen in the connective tissue.

The investigators hypothesize that treatment with topical glucocorticoids for one week before and three weeks after removal of a central venous catheter, will reduce the formation of hypertrophic scarring and keloid development in children.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01113125
Study type	Interventional
Source	Aarhus University Hospital
Contact
Status	Active, not recruiting
Phase	Phase 3
Start date	March 2010
Completion date	July 2016

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00993005` - CICATRIX in the Treatment of Hypertrophic Scars and Keloids Scars	Phase 3
Withdrawn	`NCT02546076` - Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars	Phase 2
Withdrawn	`NCT01858038` - Gene Expression During Surgical Scar Remodeling by Fractional Photothermolysis	N/A
Active, not recruiting	`NCT04389619` - Fractional Microneedling RF vs Intralesional Steroid With & Without Microneedling in Hypertrophic Scars	N/A
Active, not recruiting	`NCT00849004` - Prevention of Hypertrophic Scars or Keloids	N/A
Completed	`NCT00142441` - Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye Laser	N/A
Completed	`NCT01078428` - Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars	Phase 4
Withdrawn	`NCT02655211` - Laser Induced Bioengineered Remodeling of Thermally Injured Skin Trial	N/A
Completed	`NCT02487212` - Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery	Phase 4
Active, not recruiting	`NCT04532840` - Effect of Cryotherpy on Hypertrophic Scar	Phase 2/Phase 3
Recruiting	`NCT00548210` - Effectivity of Dermatix in Promoting Scar Maturation	Phase 3