Hypertrophic Scars Clinical Trial
Official title:
Dermatix; A Randomized Controlled Trial Measuring Effectivity of Dermatix in Promoting Scar Maturation of Hypertrophic Scars.
The purpose of this research is to demonstrate effectivity of Dermatix in promoting maturation of the scar, versus a control region that will be treated with an indifferent cream.
The healing of deep thermal injuries is always associated with scarring. The healing process
can lead to the formation of large scar bundles (e.g. hypertrophic scars). The scars can be
discomforting, disfiguring and restrict motion if situated over or near joints. Evidence for
effectivity of treatment for reduction of hypertrophic scars or the prevention of them is
limited.
Different treatments are used such as intralesional injected steroids, topically used oily
creams, silicone sheets or occlusive dressings. Compression garments are also frequently
used. There is some evidence as to the effectivity of silicone sheets for recuction of
hypertrophic scarring, however, these sheets cannot be used easily on all anatomical
locations.
Valeant Pharmaceuticals International has developed a silicone based scar remodelling gel,
Dermatix®, which has been empirically shown by others to have potential to reduce
hypertrophic scars.
Primary objectives are to demonstrate effectivity of Dermatix in promoting maturation of the
scar, versus a control region that will be treated with an indifferent cream.
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Time Perspective: Prospective
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Completed |
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