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Hyperthyroidism clinical trials

View clinical trials related to Hyperthyroidism.

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NCT ID: NCT05252884 Not yet recruiting - Thyroid Cancer Clinical Trials

Calcium+Calcitriol Versus PTH for the Prevention of Hypocalcemia in Thyroidectomy. Randomized Clinical Trial

Start date: March 30, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to compare the frequency of post-thyroidectomy symptomatic and biochemical hypocalcaemia between the strategy of routine prophylactic calcium + calcitriol vs the administration of calcium guided by PTH values.

NCT ID: NCT05142904 Recruiting - Clinical trials for Radiofrequency Ablation

Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules

RABITO
Start date: November 17, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare treatment of hyperthyroidism with radiofrequency ablation or I-131 for solitary autonomous thyroid nodules.

NCT ID: NCT05118542 Completed - Graves Disease Clinical Trials

Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis

Start date: January 1, 2019
Phase: Phase 3
Study type: Interventional

During July 2019 to August 2020, a single-blind clinical trial was done to 36 patients with Graves' disease. At the beginning of the study, subjects were accommodated into 2 groups, 17 into PTU groups and 19 into methimazole groups. There were 24 subjects who finished the study, 13 from PTU group and 11 from methimazole group. Blood serum was collected for HOMA-IR, LDL-R, NFĸB, sICAM-1, sVCAM-1 and sE-selectin examination. Meanwhile stiffness and thickness of carotid artery was measured using PWV and cIMT.

NCT ID: NCT05098600 Completed - Clinical trials for Rheumatoid Arthritis

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Start date: October 15, 2021
Phase:
Study type: Observational

The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a dermatology clinic of a metropolitan hospital.

NCT ID: NCT05070091 Completed - COVID-19 Clinical Trials

The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.

ENDO-COVID19
Start date: January 26, 2021
Phase:
Study type: Observational

The main focus of the study is the assessment of hormonal function in the course of COVID-19 infection with special regard for trends predicting clinical events defined as primary endpoints of the study.

NCT ID: NCT05049551 Completed - Hyperthyroidism Clinical Trials

Thyroid Uptake Quantification on a New Generation of Gamma Camera

QUANTHYC
Start date: October 30, 2019
Phase:
Study type: Observational

The primary objective of this study is to evaluate the potential of a new large field CZT gamma camera to estimate the thyroid uptake (TU) on Single photon emission computed tomography (SPECT) and SPECT/CT images in comparison with standard planar scintigraphy. The secondary objective is to analyze the diagnostic contribution of SPECT/CT imaging.

NCT ID: NCT04946123 Recruiting - Hyperthyroidism Clinical Trials

Hyperthyroidism: Methimazole Plus L-carnitine and Selenium

Start date: July 5, 2021
Phase: N/A
Study type: Interventional

The study aims to investigate the benefits of methimazole treatment in patients with hyperthyroidism, associated with supplementation of L-carnitine and Selenium.

NCT ID: NCT04932135 Completed - Graves Disease Clinical Trials

Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism

PULSAR
Start date: June 8, 2021
Phase:
Study type: Observational

The investigators want to investigate if a continuous heart rate monitoring with a wrist worn fitnesstracker can be useful in the treatment and surveillance of patients suffering from Graves' disease.The aim of our research project is two-fold: First, to evaluate the use of continuous heart rate monitoring as a potential substitute for hormone measurements during treatment of hyperthyroidism. Second, to use continuous heart rate monitoring as a tool for early detection of relapse after discontinuation of antithyroid drugs.

NCT ID: NCT04922801 Completed - Clinical trials for Neuroendocrine Tumors

Optimising Molecular Radionuclide Therapy

SELFIE
Start date: December 9, 2021
Phase:
Study type: Observational [Patient Registry]

This project will examine the role of the whole body, PET and SPECT imaging before, during and after radionuclide treatment for 177Lu-Dotatate therapy, whole body and SPECT imaging for 131-I for thyroid cancer therapy, and whole-body imaging for 131I for hyperthyroidism therapy. Whole-body and SPECT images will be linked to personal dosimeter readings to determine whether - Current radiation protection advice for patients receiving radionuclide treatment is appropriate. - Radiopharmaceutical retention and/or SUV change in patients undergoing repeated radionuclide treatments. - Data combined from early (quantitative imaging) and late (whole-body dose rate measurements) could support individual treatment planning for patients undergoing repeated cycles of molecular therapy.

NCT ID: NCT04879173 Recruiting - Clinical trials for Hyperthyroidism/Thyrotoxicosis

Clinical Value of Microvascular Ultrasonography in Real-time Differential Diagnosis of Thyrotoxic Patients

Start date: October 14, 2020
Phase:
Study type: Observational

This study aims to verify the clinical value of thyroid ultrasound with microvascular flow imaging in thyrotoxic patients for differential diagnosis between hyperthyroidism and thyroiditis. We intend to use the RS85 Ultrasound device manufactured by Samsung Medison. Graves' disease and painless thyroiditis/subacute thyroiditis are the main cause of thyrotoxicosis. Precise discrimination between Graves' disease and painless thyroiditis/subacute thyroiditis is clinically very important in determining treatment methods, such as the prescription of antithyroid drugs. Primary endpoint was to verify the value of vascularity index, defined by Blood pixel in range of image / Total pixel in range of image .Seondary endpoint was to verify the superiority value of Microvascular flow imaging to discriminate thyrotoxicosis patients compared with Color doppler/ Power doppler ultrasound imaging and conventional ultrasound imaging.