Hypertension Clinical Trial
Official title:
Genetics and Genomics of Hypertension Associated With Microinflammation, Oxydative Stress, Chronic Renal Disease and Heart Failure (A2-B2-B3)
This project aims at investigating the genetic, genomic and proteomic basis of hypertension and susceptibility to hypertension-related end organ damage (renal damage and heart failure). It will include cross sectional as well as follow-up studies with a large number of subjects and variety of phenotypes, to explore the pathophysiology of hypertension and hypertension-related disease.
In all index patients and recruited family members, recorded data will include the following
:
- Past medical history, drug history and family history
- Physical examination
- Height, weight, waist and hip circumference
- Cardiac examination
- Vascular examination
- Blood pressure
- Plasma and urine samples
- Body composition (DEXA)
- Tissue Doppler imaging
;
Intervention Model: Single Group Assignment, Masking: Open Label
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