Hypertension Clinical Trial
Official title:
Cardiovascular Consequences of Obstructive Sleep Apnea (OSA): Role of Endothelin and Preventive Effects of Bosentan
The study will compared the effects of bosentan, an endothelin receptor antagonist, and
nasal continuous positive airway pressure (nCPAP), obstructive sleep apnea current reference
treatment, on diastolic blood pressure in untreated mildly hypertensive sleep apnea
patients.
The hypothesis is that blocking endothelin receptors with a drug will have the same systemic
blood pressure lowering effect than nCPAP in sleep apnea patients.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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