Serum Biomarkers for Portal Hypertension in Cirrhosis (Pan-CHESS1802)

Status Recruiting

Clinical Trial Summary

This is a prospective, multi-center diagnostic trial conducted at 6 liver centers in China designed to study the correlation between serum biomarkers associated with endothelial dysfunction and immune inflammation and hepatic venous pressure gradient in cirrhosis.

Clinical Trial Description

Hepatic venous pressure gradient (HVPG) is the gold standard for assessing portal pressure, of which the measurement is invasive and therefore not suitable for routine clinical practice. The detection of serum biomarkers is potential for noninvasive diagnosis of portal hypertension in cirrhosis. However, many are still in the exploratory phases of testing and are not yet ready to enter clinical practice. This study prospectively enrolled participants in 6 liver centers (Beijing YouAn Hospital, Shandong Provincial Hospital, Beijing Shijitan Hospital, Beijing Friendship Hospital, Xingtai People's Hospital, and 302 Hospital of PLA) in China designed to study the correlation between serum biomarkers associated with endothelial dysfunction and immune inflammation and HVPG in cirrhosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03713606
Study type	Observational
Source	Nanfang Hospital of Southern Medical University
Contact	Xiaolong Qi, M.D.
Phone	+86 18588602600
Email	qixiaolong@vip.163.com
Status	Recruiting
Phase
Start date	September 30, 2018
Completion date	June 1, 2022

View Details

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