The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women

Hypertension Clinical Trial

Official title:

The Effects of a 12-week Stair Climbing Regimen on Arterial Stiffness, BP and Leg Strength in Stage-1 Hypertensive Postmenopausal Women

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03254251
• Other study ID #: PusanNU-3
• Status: Completed
• Phase: N/A
• Start date: January 9, 2017
• Est. completion date: April 10, 2017

Study information

• Verified date: October 2020
• Source: Pusan National University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or non-exercising control group. SC training session was progressive program, and was performed 4 days a week for 12 weeks. Measurements were collected at baseline and after 12 weeks during the same time of day (±1 hour) in the morning following an overnight fast and abstinence from caffeinated drinks, alcohol, and between 48 and 72 hours after the last exercise session.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 41
• Est. completion date: April 10, 2017
• Est. primary completion date: April 3, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 58 Years to 60 Years

Eligibility

Inclusion Criteria:

• Stage-1 hypertension
• Postmenopausal

Exclusion Criteria:

• Pulmonary, renal, adrenal, pituitary, severe psychiatric, thyroid, or cardiovascular disease other than stage-1 systolic hypertension (140-159 mmHg)
• Hormone replacement therapy during the 6 months prior the study
• Smoker or having any medication changes in the previous year
• Experience with psychological and physical therapy in the previous year
• History of steady exercise or exercise training in the last year

Related Conditions & MeSH terms

• Hypertension
• Menopause

Intervention

Behavioral:
• Stair climbing
Stair climbing (SC) training was 12 weeks of progressive SC program. Each training session consisted of a general warm-up (5 min: slow and fast skipping, stretching) followed by the SC training and was supervised by experienced personnel. The program began with two bouts of stair climbing four days a week in weeks 1 and 2, increasing by one climb a day every three weeks. By the last three weeks (10-12) of the study, all subjects were completing 5 climbs four days a week. During each climb participants ascended 12 flights (192 steps) divided into 3 sets of 4 flights, with a 2 min rest period between each set. There was a 5 min rest period between climbs that allowed the participants to reach the ground floor using an elevator. Subjects in the non-exercising control group did not participate in a supervised exercise program for the duration of the study.

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
Pusan National University	Dong-Eui University, University of Nebraska

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Arterial stiffness	Arterial stiff ness was measured by brachial to ankle pulse wave velocity (baPWV, m/s) using volume plethysmographic device (VP-1000).	12 weeks
Primary	Blood pressure (BP)	BP (mmHg) was measured by volume plethysmographic device. Diastolic blood pressure and systolic blood pressure were measured.	12 weeks
Primary	Muscle strength	Muscle strength was measured by the eight repetition maximum (8RM) test using extension machine (Cyber 6000).	12 weeks
Primary	Body composition	Body composition was measured using eight-polar tactile-electrode impedance meter (InBody 720). Body weight (kg), fat mass (kg), and fat free mass (kg) were assessed.	12 weeks
Primary	Height	Height (m) was measured with a stadiometer	12 weeks
Primary	Heart rate (HR)	Heart rate was measured by ECG	12 weeks
Primary	Body mass index (BMI)	BMI was calculated as weight/height^2 (kg/m^2)	12 weeks