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Clinical Trial Summary

The purpose of this study is to evaluate the splenic activation in hypertensive patients, as compared to normotensives, using FDG-PET/CT imaging. Moreover, the investigators will investigate whether the splenic metabolic activity relates to the expression of circulating inflammatory proteins (high-sensitivity C-reactive protein [hsCRP]), interleukin-1b (IL-1b), tumor necrosis factor-a (TNF-a) or to immune profiles of activated T cells.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02572765
Study type Observational
Source Neuromed IRCCS
Contact Giuseppe Lembo, MD in Cardiology
Phone +39 0865.915225
Email lembo@neuromed.it
Status Not yet recruiting
Phase N/A
Start date January 2018
Completion date September 2020

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