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NCT00449111 Clinical Trial

An Open Label Study to Assess the Efficacy, Safety and Tolerability of COZAAR Plus (Losartan Potassium 50mg/Hydrochlorothiazide 12.5mg) Possibly Titrated up to COZAAR Plus-F (Losartan Potassium 100mg/Hydrochlorothiazide 25mg) in Patients With Essential Hypertension (0954A-325)

Hypertension Clinical Trial

Official title:
An Open Label Study to Assess the Efficacy, Safety and Tolerability of COZAAR Plus (Losartan Potassium 50mg/Hydrochlorothiazide 12.5mg) Possibly Titrated up to COZAAR Plus-F (Losartan Potassium 100mg/Hydrochlorothiazide 25mg) in Patients With Essential Hypertension

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00449111
Other study ID # 0954A-325
Secondary ID 2007_005
Status Terminated
Phase Phase 3
First received
Last updated
Start date March 13, 2006
Est. completion date September 30, 2006

Study information
Verified date February 2022
Source Organon and Co
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Evaluate blood pressure after 6 weeks of treatment with COZAAR plus.

Recruitment information / eligibility
Status Terminated
Enrollment 11
Est. completion date September 30, 2006
Est. primary completion date September 30, 2006
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patient treated with valsartan 80mg or irbesartan 150mg or vandesartan 8mg for at least 4 weeks prior to visit 1 - Patient with systolic blood pressure between 140 to 159 mmhg and diastolic pressure between 90 to 99mmhg taken at visit 1 Exclusion Criteria: - History of angina pectoris that has not been stabilized in the past 6 weeks - History of clinically significant abnormal lab results or diseases - Myocardial infarction within the past 6 months - Stroke in the past 6 months

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• MK0954, losartan potassium / Duration of Treatment - 12 weeks

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Organon and Co

Outcome
Type Measure Description Time frame Safety issue
Primary Change of diastolic blood pressure after 6 weeks of treatment with cozaar plus
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