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Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis

Hypertension, Renovascular Clinical Trial

Official title:
Comparison of Drug-eluting Balloon and Plain Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis: a Randomized Controlled Study

Clinical Trial Summary

Efficacy of drug eluting balloon(DEB) for non-atherosclerotic renal artery stenosis will be tested in this study. The intervention group will be treated with paclitaxel eluting balloon. The control group will be treated with plain old balloon(POB). The primary endpoint is efficacy of blood pressure control.

Clinical Trial Description

Renal artery stenosis is common cause for hypertension in young people. It could be treated with open surgery or endovascular intervention. Open surgery has relatively high complication rate. Endovascular intervention is micro-invasive but with high restenosis rate. Drug eluting balloon(DEB) has been demonstrated to be effective for preventing restenosis in peripheral arteries. This study aims to test the efficacy of drug eluting balloon for non-atherosclerotic renal artery stenosis. The intervention group will be treated with paclitaxel eluting balloon. The control group will be treated with plain old balloon. The primary endpoint is efficacy of blood pressure control. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04366596
Study type Interventional
Source Peking Union Medical College Hospital
Contact Xitao Song, MD
Phone 96-10-69152501
Email sxitao@sina.com
Status Recruiting
Phase Phase 3
Start date October 1, 2019
Completion date October 1, 2023
View Details
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