Hypertension on Emergence Clinical Trial
Official title:
Hypertensive Urgency Treatment and Outcomes in a Northeast Thai Population: The Results From the Hypertension Registry Program
Previous studies have reported a high prevalence of hypertensive (HT) urgency. However, these studies have also reported low rates of serious complications, suggesting that rapid blood pressure (BP) reduction may be unnecessary. There are limited clinical data available on this topic in Asian populations. The investigators aimed to determine the basic characteristics, treatment methods, and outcomes in HT urgency patients, both in the emergency room (ER) and at a two-week follow-up.
Previous studies have reported the high prevalence of hypertensive (HT) urgency. However,
these studies have also reported low rates of serious complications, suggesting that rapid
blood pressure (BP) reduction may be unnecessary. There are limited clinical data available
on this topic in Asian populations. The investigators aimed to determine the basic
characteristics, treatment methods, and outcomes in HT urgency patients, both in the
emergency room (ER) and at a two-week follow-up.
This was a cohort study conducted at Srinagarind hospital, a tertiary-care level university
hospital in Khon Kaen, Thailand. The data collection period was from January 2012 to June
2017. The Khon Kaen University Ethics Committee in Human Research approved the protocol.
Patients aged 18 years or older who visited the ER with a diagnosis of HT urgency were
consecutively enrolled in the study. Patients who were pregnant or lactating had secondary
causes of HT, or had incomplete medical records were excluded from the study Office BP was
measured using an upper arm cuff oscillometric BP device. The appropriate cuff size for each
individual's arm circumference was used. Three BP readings were taken at 30-second intervals
with the patient in a sitting position after five minutes of rest. The average of three BP
measurements was used for analysis.
Baseline characteristic data were shown as the mean and standard deviation (SD) or
percentage. An independent sample t-test was used to compare between groups for continuous
variables including age, body mass index (BMI), systolic blood pressure (SBP), diastolic
blood pressure (DBP), mean arterial pressure (MAP), time of treatment, and the number of
medications being administered. A probability value <0.05 was considered statistically
significant. All statistical analyses were performed with SPSS for Mac version 20.0,
registered to Khon Kaen University.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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N/A |