Pulmonary Rehabilitation in Patients With Chronic Fibrotic

Status Not yet recruiting

Clinical Trial Summary

The aim is to evaluate exercise capacity, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, physical activity level, quality of life, fatigue, dyspnea, anxiety, depression and investigate the impact of 24-session pulmonary rehabilitation training on these parameters in patients with chronic fibrotic hypersensitivity pneumonitis.

Clinical Trial Description

Hypersensitivity pneumonitis is a syndrome that results in the excessive immune response to inhalation of various antigenic particles in the environment. Patients often experience irreversible physiological disorders and severe dyspnea in the future. Common disorders in these patients are lung function abnormalities, decreased exercise capacity, muscle weakness, oxygen diffusion limitation, impaired quality of life, physical inactivity and fatigue. The aim of this study is to evaluate the effects of pulmonary rehabilitation training on exercise capacity, dyspnea, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, physical activity level, quality of life, fatigue, dyspnea, anxiety, depression in patients with chronic fibrotic hypersensitivity pneumonitis. The study was planned as a prospective, double-blind, case-control study. At least 30 patients with hypersensitivity pneumonitis will be included in the study. The cardiopulmonary rehabilitation program will be included inspiratory muscle training, upper extremity aerobic exercise and progressive resistance training will be performed in the exercise training group during 24 sessions. Alternative upper extremity exercises combined with breathing exercises will be performed in the control group. Functional exercise capacity, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, physical activity levels, quality of life, fatigue, dyspnea, anxiety and depressions will be evaluated before and after treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04561479
Study type	Interventional
Source	Gazi University
Contact	Zeliha ÇELIK, MSc
Phone	+903122162647
Email	zelihacelik@gazi.edu.tr
Status	Not yet recruiting
Phase	N/A
Start date	June 1, 2021
Completion date	June 1, 2023

View Details

See also
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Recruiting	`NCT05365802` - FAPI PET for Lung Fibrosis	Early Phase 1
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Withdrawn	`NCT04677426` - 129Xe Gas Exchange Imaging in IPF and cHP: A Reliability Study	Phase 2
Recruiting	`NCT04961944` - HypErsensitiVity PneumonITis: DiseAse Progression Characterization
Not yet recruiting	`NCT03800017` - Skeletal Muscle Function in Interstitial Lung Disease	N/A
Completed	`NCT04273867` - Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis
Completed	`NCT05723796` - Study of Nasal Mucosa Histopathological Changes in Chronic Hypersensitivity Pneumonitis	N/A
Recruiting	`NCT04402177` - This Study Aim is to Compare the Effect of Oral Methyl Prednisolone on Different Radiological Patterns of Hypersensitivity Pneumonitis as it Was Found That Not All Patients Get Satisfying Therapeutic Effect After Taking Corticosteroids.	Phase 4
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Enrolling by invitation	`NCT05727852` - Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases
Not yet recruiting	`NCT05988437` - Contribution of the Indoor Environment Medical Advisor in the Management of Fibrosing Hypersensitivity Pneumonitis
Completed	`NCT04675619` - Evaluation of the Efficacy of Pirfenidone in Progressive Chronic Hypersensitivity Pneumonitis	Phase 2
Recruiting	`NCT05392881` - Interstitial Lung Disease Research Unit Biobank
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Completed	`NCT05458635` - Predictors of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Pulmonary Rehabilitation in Patients With Chronic Fibrotic Hypersensitivity Pneumonitis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms