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Hyperplasia clinical trials

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NCT ID: NCT04947631 Completed - Clinical trials for Benign Prostatic Hyperplasia

Efficacy and Safety of DKF-313 in Patients With Benign Prostatic Hyperplasia

Start date: July 27, 2021
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blinded, double-dummy, parallel group, 48-week study to evaluated the efficacy and safety of DKF-313 (dutasteride and tadalafil) in patients with benign prostatic hyperplasia.

NCT ID: NCT04924543 Completed - Ulcerative Colitis Clinical Trials

OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD

OPTIC-IBD
Start date: July 7, 2021
Phase: N/A
Study type: Interventional

People with inflammatory bowel diseases (IBD) can be at higher risk of developing abnormal areas in their bowel. These abnormal areas can be due to active inflammation, healed inflammation, polyps or pre-cancerous changes ("dysplasia"). It is for this reason that people with IBD are offered periodic surveillance colonoscopy procedures to identify, characterize and where necessary remove abnormal areas or lesions from the bowel. These can be difficult to characterize correctly, which is important to make the correct endoscopic diagnosis and management plan. Technical advancements in endoscopy mean that more tools are available to identify and characterize these lesions in real time during colonoscopy. Specialists regularly performing gastrointestinal endoscopy and colonoscopy ("endoscopists") will often receive special training, both during their initial postgraduate training and through continuous professional development programs. This study aims to evaluate whether an online training platform can improve the ability of endoscopists to characterize dysplasia in IBD. The goal is to support improved decision-making during IBD surveillance, reporting of dysplastic lesions, and ultimately the care and outcomes of people with IBD.

NCT ID: NCT04904640 Completed - Dysplasia; Hip Clinical Trials

Biomechanical Reconstruction of Three Different Hip Stem Designs in Hip Dysplasia Using a 3D CT-based Planning Software

CTdevice
Start date: May 10, 2021
Phase:
Study type: Observational

A random population of 200 CT scans of pelvis and thigh in an adult population affected by hip dysplasia will be selected. The aim of this study is to evaluate the biomechanical reconstruction of the hip anatomy provided by three different hip stem designs in dysplastic cases, using a 3D CT based software for pre-operative planning.

NCT ID: NCT04873206 Completed - Clinical trials for Endometrial Adenocarcinoma

Diagnostic and Prognostic Value of PTEN Expression in Functional and Pathological Endometrial Biopsies

Start date: January 1, 2020
Phase:
Study type: Observational

endometrial hyperplasia may progress to endometrial adenocarcinoma. the exact possibility of such progression is not determined. there a need to detect biological markers that can help in detecting high risk cases of patients with endometrial hyperplasia that may progress to endometrial adenocarcinoma. PTEN is a tumor suppressor gene that inhibit cell migration, proliferation and may induce apoptosis in damaged cells. variable expression of PTEN in functional, hyperplastic and neoplastic endometrial tissues may be of great help in detecting cases of hyperplasia that may progress to endometrial adenocarcinoma.

NCT ID: NCT04856943 Completed - Clinical trials for Benign Prostatic Hyperplasia

Effectiveness of Smartconsent in Improving Understanding of Informed Consent

SMARTCONSENT
Start date: December 31, 2021
Phase: N/A
Study type: Interventional

The general objective of the study is to assess whether the new smartconsent tool improves patients' understanding of the intervention to be performed, compared to standard practice. A randomized clinical trial will be conducted in 50 patients who will undergo LASER PROSTATIC ENUCLEATION.

NCT ID: NCT04848181 Completed - Clinical trials for Prostate Hyperplasia

The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate

Start date: July 1, 2019
Phase: Early Phase 1
Study type: Interventional

Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss with mono polar TURP

NCT ID: NCT04831476 Completed - Clinical trials for Benign Prostatic Hyperplasia

Α Prospective Observational Study for the Evaluation of Disease Control and Quality of Life in Patients With Benign PROStatic hyPERplasia Under Fixed Dose combΙnaTion Treatment With Dutasteride and Tamsulosin . PROSPERITY Group of Studies (I&II)

PROSPERITY
Start date: September 1, 2021
Phase:
Study type: Observational

Investigation of the efficacy and safety of the stable combination of dutasteride and tamsulosin (Dinaplex®) in the Greek population as well as the evaluation of the quality of life of patients with benign prostatic hyperplasia (BPH) in treatment with a stable combination of dutasteride and tamsulosin (Dinaplex®)

NCT ID: NCT04823221 Completed - Clinical trials for Benign Prostatic Hyperplasia (BPH)

To Evaluate the Feasibility, Preliminary Safety and Performance of Rezūm System in BPH Treatment in China

Start date: July 10, 2021
Phase:
Study type: Observational

A real world study to evaluate the feasibility, preliminary safety and performance of Rezūm system in BPH treatment in China Rezūm RWS study

NCT ID: NCT04781985 Completed - Clinical trials for Prostate Hyperplasia

Prostatic Resection Cavity Stone Post Transurethral Resection of the Prostate (TURP). A Rare Case Scenario

prostatic
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Prostatic resection cavity stone post transurethral resection of the prostate (TURP). A rare case scenario

NCT ID: NCT04781049 Completed - Clinical trials for Benign Prostatic Hyperplasia

Transperineal Laser Ablation vs Transurethral Resection for Benign Prostatic Obstruction: A Randomized Clinical Trial

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The primary objective of the study is to compare Trans-Perineal Laser Ablation of Prostate versus Trans-Urethral Resection of Prostate in the immediate impact on post-operative pain; in terms of relief in benign prostatic obstruction and preservation of the ejaculatory function in the short term (at 1, 3 and 6 months). The secondary objective of the study is the evaluation of the long-term deobstructive effectiveness (12 months).