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Hyperkalemia clinical trials

View clinical trials related to Hyperkalemia.

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NCT ID: NCT06281470 Completed - Hyperkalemia Clinical Trials

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Start date: February 13, 2023
Phase: Phase 1
Study type: Interventional

This clinic trial evaluates the safety and tolerability of single- and multiple- ascending doses of WS016 in healthy adult participants. There will be about 64 participants,48 active and 16 placebo.

NCT ID: NCT05860491 Completed - Hyperkalemia Clinical Trials

Dietary Fiber and Hyperkalemia in Dialysis Patients

Start date: January 1, 2022
Phase:
Study type: Observational

To analyze the dietary nutrition and dietary fiber (DF) intake of maintenance hemodialysis (MHD) patients, and explore the effect of dietary nutrition and DF intake balance on the nutritional status and pre-dialysis hyperkalemia of MHD patients.

NCT ID: NCT05462119 Completed - Hyperkalaemia Clinical Trials

Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency

SCRUTINIZE
Start date: August 22, 2022
Phase:
Study type: Observational

It is a multicenter, prospective, non-interventional cohort study, in order to evaluate the safety of oral resin for treatment of hyperkalemia in Chinese patients with renal insufficiency.

NCT ID: NCT05441852 Completed - Hyperkalemia Clinical Trials

A Study to Detect Hyperkalemia Using Smartphone-enabled Electrocardiogram (EKG)

REACT
Start date: March 31, 2022
Phase:
Study type: Observational

The purpose of this study is to validate the real-world performance of a previously developed Artificial Intelligence - Electrocardiogram (AI-ECG) algorithm for identification of hyperkalemia with a six-lead mobile-enhanced device .

NCT ID: NCT05382988 Completed - Hyperkalemia Clinical Trials

Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy

SZC
Start date: November 2016
Phase: Phase 3
Study type: Interventional

Sodium zirconium cyclosilicate (SZC) has been demonstrated for its serum potassium-lowering efficacy and safety in hyperkalemia hemodialysis patients. However, the effects of SZC during the perioperative period remained unknown. This experiment aimed to determine whether using SZC would impact the serum potassium levels in patients with maintenance hemodialysis after parathyroidectomy (PTX).

NCT ID: NCT05184998 Completed - Heart Failure Clinical Trials

Description of the Clinical Outcomes of Hospitalized Patients With Heart Failure With Different Serum Potassium Levels

SPLENDID
Start date: November 30, 2021
Phase:
Study type: Observational

China National Heart Failure Registration Study (CN-HF) is a nationwide, hospital-based, multicentre, prospective registry study sponsored by Ministry of Science and Technology of the People's Republic of China. It is aimed to understand the etiology, clinical features and treatments of in-hospital HF patients in China [3]. At present, there are few studies to describe the clinical outcomes of HF patients with different sK levels in China. Utilizing the CN-HF database, this study is aimed to describe the sK levels of hospitalized HF patients and its impact to the clinical outcomes of patients.

NCT ID: NCT05118022 Completed - Hyperkalemia Clinical Trials

Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE)

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial (RCT) to test a novel artificial intelligence (AI)-enabled electrocardiogram (ECG)-based screening tool for improving the diagnosis and management of potassium abnormalities.

NCT ID: NCT05029310 Completed - Kidney Transplant Clinical Trials

Effects of Patiromer on Pharmacokinetics of Immunosuppresive Drugs in Renal Transplant Recipients

TACPAT
Start date: September 1, 2021
Phase: Phase 4
Study type: Interventional

Patiromer lowers potassium effectively in patients with hyperkalemia and chronic kidney disease. Patients with a kidney transplant usually have reduced renal function and may also develop hyperkalemia. However, potential interactions between immunosuppressive medications and patiromer have not been evaluated. These interactions could involve change in AUC of immunosuppressive drugs, such as calcineurin inhibitors or mycophenolate, or increased risk of hypomagnesemia, since both tacrolimus and patiromer have this potential side effect. We wish to evaluate potential interactions to ensure safe use of this drug in the transplant population.

NCT ID: NCT04955678 Completed - Hyperkalemia Clinical Trials

A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia

Start date: August 3, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the superiority of ZG-801 to placebo in Japanese hyperkalemia patients whose serum potassium value becomes normal in the Run-in period by comparing the change in the value at the Double-blind period week 4, and to further evaluate the efficacy and safety of ZG-801 in Japanese hyperkalemia patients administrated ZG-801 for maximum 9 weeks.

NCT ID: NCT04799067 Completed - Hemodialysis Clinical Trials

Hyperkalaemia Prevalence, Recurrence and Treatment in Haemodialysis

PRECEDE-K
Start date: May 17, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the prevalence and recurrence of Hyperkalaemia (HK) in Chinese HD patients and to understand the treatment pattern of HK in China.