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Hypercholesterolemia clinical trials

View clinical trials related to Hypercholesterolemia.

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NCT ID: NCT00136981 Completed - Hyperlipidemia Clinical Trials

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

RADIANCE 1
Start date: December 2003
Phase: Phase 3
Study type: Interventional

The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To look at ultrasound images taken in the carotid arteries and to look at various lipids in the blood of people with heterozygous familial hypercholesterolemia

NCT ID: NCT00136799 Completed - Clinical trials for Hypercholesterolemia

Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of fluvastatin 80 mg in a Chinese population. This study is not recruiting patients in the US.

NCT ID: NCT00134511 Completed - Clinical trials for Hypercholesterolemia, Familial

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To evaluate the efficacy and safety of the lipid drug Torcetrapib/atorvastatin in patients with genetically known disorder of extremely high cholesterol

NCT ID: NCT00134485 Completed - Hyperlipidemia Clinical Trials

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To evaluate the efficacy and safety of torcetrapib/atorvastatin compared to atorvastatin alone in patients with heterozygous familial hypercholesterolemia

NCT ID: NCT00133380 Completed - Clinical trials for Hypercholesterolemia

A Study in People With High Cholesterol

Start date: July 2005
Phase: Phase 2
Study type: Interventional

The purposes of this study are to determine: - The safety of the study medication and any side effects that might be associated with it - Whether the study medication can help patients with high levels of "bad" cholesterol (low-density lipoprotein-cholesterol [LDL-C]), alone or in combination with additional study medication

NCT ID: NCT00133094 Completed - Clinical trials for Hypercholesterolemia

Systematic Management of High Cholesterol Utilizing Computer Monitoring

Start date: June 2006
Phase: N/A
Study type: Interventional

Employing a physician-directed case management system, utilizing a Certified Registered Nurse Practitioner (CRNP) in conjunction with computer-based decision support technology (CDST) will result in significantly lower total cholesterol and a lower low density lipoprotein cholesterol in a group of subjects enrolled in a general medical clinic compared to subjects managed by primary care providers in the usual care group.

NCT ID: NCT00132717 Completed - Clinical trials for Hypercholesterolemia

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Start date: January 1, 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of an investigational cholesterol-lowering drug in patients who are currently taking an approved medication for hypercholesterolemia (high cholesterol levels) and have been hospitalized for a heart problem.

NCT ID: NCT00129402 Completed - Clinical trials for Hypercholesterolemia

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Start date: August 2005
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, controlled, parallel-group, multicenter, Phase-3 study to evaluate the efficacy and safety of ezetimibe with simvastatin taken alone in subjects ages 10-17 years with Heterozygous Familial Hypercholesterolemia.

NCT ID: NCT00120718 Completed - Atherosclerosis Clinical Trials

The Effect of Fasudil on Vascular Function in Humans

Start date: June 2002
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate how the rho kinase inhibitor, fasudil, affects vascular function in patients with atherosclerosis and hyperlipidemia.

NCT ID: NCT00115232 Completed - Inflammation Clinical Trials

Inflammatory Profiles of Children at High Risk for Atherosclerosis

Start date: July 2004
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate levels of inflammatory mediators in children at risk for cardiovascular disease due to family history. We are measuring inflammatory markers in two groups of children and their parents: children with a family history of early atherosclerotic heart disease (cases), and healthy children without such a family history (controls). The design is a cross-sectional study, gathering a fasting blood sample and clinical and behavioral data on children and a parent.