Microbiome Composition Changes on 4 Week Gluten-free Diet Challenge

Status Completed

Clinical Trial Summary

Changes in the gut microbiomes of healthy volunteers who followed a gluten-free diet (GFD) for four weeks were studied. Per participant, nine stool samples were collected: one at baseline, four during the GFD period, and four when they returned to their habitual diet. Microbiome profiles were determined using 16S rRNA sequencing and the samples were next processed for taxonomic and imputed functional composition. Additionally, participants kept a 3-day food diary and six gut health-related biomarkers were measured.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Human Microbiome

Clinical Trial Details

NCT number	NCT02731976
Study type	Interventional
Source	University Medical Center Groningen
Contact
Status	Completed
Phase	N/A
Start date	November 2011
Completion date	May 2014

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