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Quantitative HPV Genotyping in Screening of Anal Intraepithelial Neoplasia in HIV-positive Patients — GAIN  

Human Immunodeficiency Virus Clinical Trial

Official title:
Quantitative HPV Genotyping in Screening of Anal Intraepithelial Neoplasia in HIV-positive Patients

Clinical Trial Summary

The pathophysiology from anal HPV infection to Anal Intraepithelial Neoplasia is less well understood than cervical HPV infection. In cervical screening programs it is well accepted that the sole presence of a high-risk HPV strain (irrespective of number of viral particles) is sufficient to justify further investigation and treatment. The investigators hypothesize that in anal HPV infection not only the presence but the extent of HPV infection (single genotype viral load) or combination of different HPV genotypes (cumulative viral load) is of importance in determining the risk of anal dysplasia.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03742375
Study type Interventional
Source Universitaire Ziekenhuizen Leuven
Contact
Status Terminated
Phase N/A
Start date August 1, 2018
Completion date November 1, 2020
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