Human Immunodeficiency Virus Clinical Trial
Official title:
Supporting Adolescents to Adhere - an Intervention Using Airtime Rewards Allocated by a Prize Drawing
This study is an extension of Reminding Adolescents to Adhere (RATA) (Unique protocol ID:
1R01HD074925-01). Participants for SATA will be recruited during the RATA month 24 exit
survey.
Participants will be randomized 1:1:1 into either one of two intervention group (receiving
the weekly messages and a chance to draw a prize at each clinic visit based on either a fixed
adherence level of 90% or a self-chosen one of at least 80% as further detailed below) or the
control group that receives the existing RATA intervention consisting of weekly motivational
messages and the chance to get mobile airtime rewards conditional on responding. Doing so
will allow the investigators to cleanly evaluate the impact of these additional
adherence-based lotteries, and guarantees that those who have been in the control group
receiving standard of care in the first 24 months of the RATA intervention will also receive
an intervention for reasons of fairness.
- For Group 1 (lottery reward with fixed target): Study coordinators check participant's
MEMS extraction for last month's adherence. Study coordinators then tell participants of
the participants' adherence in the last month. Participants are also informed that
during the next clinic visit, if they adhere at least 90 percent they have a chance to
enter into a game where they have a chance of winning mobile airtime, by drawing into a
bag and picking a card associated with their airtime winnings. If they do not have 90%
adherence, they will not receive the airtime award game, but there will be another
chance the next time they come for their scheduled clinic visit during the study period.
- For Group 2 (lottery award with own target): Study coordinators check participant's MEMS
extraction for last month's adherence. They inform participants of their adherence in
the last month. In order to be eligible for an airtime reward game, during their next
clinic visit they must reach their own target goal. The target adherence goal must be
greater than 80%. Participants may, for example, choose 80%, 85%, 90%, 95%, or 100%.
Again, if they meet or exceed this target they have a chance to draw into a bag to win
mobile airtime. If they do not have meet this self-imposed target adherence, they will
not be eligible to play the airtime award game, but there will be another chance the
next time they come for their scheduled clinic visit during the study period.
During each clinic visit, participants will have their MEMS extracted and study coordinators
will check for average adherence between that day and the last clinic visit. For those who
have met the target, coordinators will initiate the lottery, complete the drawing procedure,
or send them the airtime reward without drawing (depending on which group).
Every Sunday, study investigators will send treatment participants a motivational message to
remind them about the reward. Within each of the two intervention groups, study investigators
will randomly send the message either in a loss-frame or a gain-frame, i.e. an intervention
participant (in either group) will some weeks receive a message telling them to keep up
motivation (as a code-word for adherence) to win a prize, and some weeks telling them to make
sure not to lose their chance to win a prize.
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