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Hot Flashes clinical trials

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NCT ID: NCT01245907 Terminated - Menopause Clinical Trials

Climacteric Therapy With Applied Relaxation Using InterNet

CARIN
Start date: February 2011
Phase: N/A
Study type: Interventional

The aim is to evaluate effects of internet-based applied relaxation (a simplified version of cognitive behavioral therapy) for women with menopausal symptoms mainly vasomotoric symptom (VMS), i.e. hot flashes and sweating. Sixty postmenopausal women with VMS will be recruited and 30 randomized to applied relaxation (AR) via internet and 30 to a control group which is a non-treated waitlist group. At baseline, after 10 weeks of therapy and six, 12 and 24 months after end of therapy women will be asked to fill in diaries about hot flashes and answer questionnaires on Quality of Life (Women's Health Questionnaire; WHQ, anxiety and depression measured with Hospital Anxiety and Depression Scale; HADS and one measuring sleep, Insomnia Severity Index; ISI as well as one about knowledge of the climacteric and hormone therapy). The waiting list group will be offered internet based AR after 10 weeks with the same follow-up as the treatment group.

NCT ID: NCT01126801 Terminated - Clinical trials for Menopausal Depression

Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women

Start date: May 2010
Phase: Phase 2
Study type: Interventional

This protocol is a controlled study of estradiol therapy in early postmenopausal women with and without frequent hot flashes that will be used to determine whether hot flashes are an important intermediary in the generation of menopause-associated depression.

NCT ID: NCT00594620 Terminated - Prostate Cancer Clinical Trials

Soy Derivatives for Control of Hot Flashes in Men on Androgen Deprivation Therapy

Start date: August 2004
Phase: Phase 2
Study type: Interventional

To determine the efficacy of soy/isoflavone supplementation on hot flashes in men who are being treated with luteinizing hormone-releasing hormone (LHRH) agonist therapy for control of advanced prostate cancer

NCT ID: NCT00354432 Terminated - Prostate Cancer Clinical Trials

Soy Protein/Effexor Hormone Therapy for Prostate Cancer

Start date: February 1, 2007
Phase: Phase 3
Study type: Interventional

RATIONALE: Soy protein/isoflavones and venlafaxine may help relieve hot flashes in patients receiving hormone therapy for prostate cancer. It is not yet known whether soy protein/isoflavones are more effective than venlafaxine when given together or with a placebo in treating hot flashes. PURPOSE: This randomized phase III trial is studying soy protein/isoflavones and venlafaxine to compare how well they work when given together or with a placebo in treating hot flashes in patients receiving hormone therapy for prostate cancer.

NCT ID: NCT00288262 Terminated - Hot Flashes Clinical Trials

Melatonin Effects on Luteinizing Hormone

Start date: June 2004
Phase: Phase 1/Phase 2
Study type: Interventional

In many mammals, the duration of the nocturnal melatonin elevation regulates seasonal changes in reproductive hormones such as luteinizing hormone (LH). Melatonin's effects on human reproductive endocrinology are uncertain. It is thought that the same hypothalamic pulse generator may both trigger the pulsatile release of GnRH and LH and also cause hot flashes. Thus, if melatonin suppressed this pulse generator in postmenopausal women, it might moderate hot flashes. This clinical trial tested the hypothesis that melatonin could suppress LH and relieve hot flashes.

NCT ID: NCT00249847 Terminated - Hot Flashes Clinical Trials

Study of PET Scans and Serotonin in Hot Flashes Treatment

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine in a preliminary manner whether successful therapy of hot flashes can be associated with changes in the serotonin transporter in the brain. The serotonin transporter is important in delivering serotonin into certain portions of the brains (serotonin is a chemical that is important in the control of body temperature, mood, sleep, and other functions).

NCT ID: NCT00244894 Terminated - Prostate Cancer Clinical Trials

Acupuncture in Treating Hot Flashes in Patients With Prostate Cancer

Start date: September 2002
Phase: N/A
Study type: Interventional

RATIONALE: Acupuncture may help relieve hot flashes in patients with prostate cancer. PURPOSE: This clinical trial is studying how well acupuncture works in treating hot flashes in patients with prostate cancer who are undergoing androgen deprivation.

NCT ID: NCT00217074 Terminated - Hot Flashes Clinical Trials

Acupuncture and Hot Flashes

Start date: January 2004
Phase: Phase 3
Study type: Interventional

Methods: 103 participants, after being randomized to medical versus sham acupuncture received bi-weekly treatments for 5 weeks, after a baseline assessment week. They were then followed for an additional 7 weeks. Participants completed daily hot flash questionnaires, which formed the basis for analysis.

NCT ID: NCT00110136 Terminated - Breast Cancer Clinical Trials

St. John's Wort in Relieving Hot Flashes in Postmenopausal Women With Non-Metastatic Breast Cancer

Start date: March 16, 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: St. John's wort may help relieve hot flashes in women with breast cancer. PURPOSE: This phase II trial is studying how well St. John's wort works in relieving hot flashes in women with non-metastatic breast cancer.

NCT ID: NCT00068185 Terminated - Hot Flashes Clinical Trials

A Study of the Pharmacokinetics of Black Cohosh

Start date: August 2003
Phase: Phase 1
Study type: Interventional

Black cohosh is a natural supplement that has been used to treat and prevent menopausal symptoms. Remifemin is a standardized form of black cohosh. The purpose of this study is to determine the levels of components of black cohosh obtained in the blood of healthy women taking Remifemin.